Assistant Director of Clinical Genomics Laboratory, Center for Personalized Medicine (CPM)
Attending Physician
Assistant Professor of Clinical Pathology, Keck School of Medicine of USC
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Dr. Matthew Hiemenz is an Assistant Professor of Clinical Pathology, Keck School of Medicine of the University of Southern California, and Assistant Director of the Clinical Genomics Laboratory in the Center for Personalized Medicine in the Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles. Dr. Hiemenz received his M.D. and M.S. (in Genetics) from the University of Texas Southwestern Medical Center where he also completed residency training in anatomic and clinical pathology. He completed a clinical fellowship in molecular genetic pathology and a post-doctoral fellowship in genomic test development at the Hospital of the University of Pennsylvania. He focuses on molecular oncology as well as testing for inherited disorders using next-generation sequencing and microarray technologies.

Clinical Interests

Molecular Oncology
Next-Generation Sequencing for Inherited Disorders
Integration of Genomic Data into the Practice of Medicine


Medical School: 

University of Texas Southwestern Medical Center


University of Texas Southwestern Medical Center (Anatomic and Clinical Pathology)


Hospital of the University of Pennsylvania (Molecular Genetic Pathology)



American Board of Pathology: Anatomic and Clinical Pathology
American Board of Medical Genetics and Genomics: Molecular Genetic Pathology
American Board of Pathology: Molecular Genetic Pathology

Professional Memberships: 

American Medical Association
Association for Molecular Pathology
College of American Pathologists


Arthur G. Weinberg, M.D. Resident Research Award

Other Information


Hiemenz MC, Kadauke S, Lieberman DB, Roth DB, Zhao J, Watt CD, Daber RD, and Morrissette JJ. Building a Robust Tumor Profiling Program: Synergy Between Next-Generation Sequencing and Targeted Single-Gene Testing. PLoS One. 11: e0152851, 2016. PMID 27043212

Hatanpaa KJ, Hu T, Vemireddy V, Foong C, Raisanen JM, Oliver D, Hiemenz MC, Burns DK, White CL III,Whitworth LA, Mickey B, Stegner M, Habib AA, Fink K, Maher EA, Bachoo RM. High expression of the stem cell marker nestin is an adverse prognostic factor in WHO grade II-III astrocytomas and oligoastrocytomas. J Neurooncol. 117: 183-9, 2014. PMID 24519516, PMCID 4326086

Hiemenz MC, Leung ST, Park JY. Crossing Boundaries: A comprehensive survey of medical licensing laws and guidelines regulating the interstate practice of pathology. Am J Surg Pathol. 38: e1-5, 2014. PMID 24525516

Hiemenz MC, Chen W, Winnick N, Garcia R, Tirado C. Coexistence of t(12;21)(p13;q22)/ETV6-RUNX1 and 11q23/MLL rearrangements in B lymphoblastic leukemia. J Assoc Genet Technol. 37: 213-5, 2011. PMID 20594592

Tirado CA, Chen W, Huang LJ, Laborde C, Hiemenz MC, Valdez F, Ho K, Winnick N, Lou Z, Koduru P. Novel JAK2 rearrangement resulting from a t(9;22)(p24;q11.2) in B-acute lymphoblastic leukemia. Leuk Res. 34: 1674-6, 2010. PMID 20594592

Research Interests: 

Classification of rare or unusual variants, especially somatic variants
Validation of genomic tests in a variety of indications including minimal residual disease
Pathology informatics
Optimizing communication of genetic data

Children's Hospital Los Angeles

4650 Sunset Blvd.
Los Angeles, CA 90027
Phone: 877-543-9522Office