Attending Neonatologist
Clinical Assistant Professor of Pediatrics (Clinician Educator), Keck School of Medicine of USC
  • Summary
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Leah Yieh, MD, MPH is an attending neonatologist in the Division of Neonatology at Children’s Hospital Los Angeles and is an Assistant Professor of Clinical Pediatrics at the Keck School of Medicine of the University of Southern California. Her research focus involves using decision-analytic modeling and cost-effectiveness analysis to understand the clinical and financial implications of interventions at the population level in order to optimize resource utilization and provide a framework for standardized clinical practices.

Education

Medical School: 

University of Texas School of Medicine

Internship: 

Oregon Health & Science University

Residency: 

Oregon Health & Science University

Fellowship: 

Oregon Health & Science University

Accomplishments

Certification: 

American Board of Pediatrics, General Pediatrics

Professional Memberships: 

Section on Perinatal Pediatrics, American Academy of Pediatrics
International Society for Pharmacoeconomics and Outcomes Research
Society for Medical Decision Making
Western Society for Pediatric Research

Funding

K12 Pediatrician-Scientist Research Career Development Award, Children’s Hospital Los Angeles

Publications: 

Yieh L, Dukhovny D, Zhou CG, Caughey AB. Cost-Effectiveness of Neonatal Resuscitation at 22 Weeks of Gestation. Obstetrics & Gynecology. 2019 Jun;133(6):1199-1207. doi: 10.1097/AOG.0000000000003264.

Yieh L, McEvoy CM, Hoffman SW, Caughey AB, MacDonald KD, Dukhovny D. Cost-effectiveness of vitamin C supplementation for pregnant smokers to improve offspring lung function at birth and reduce childhood wheeze/asthma. Journal of Perinatology. 2018 May 22. doi: 10.1038/s41372-018-0135-6.

Yieh L, Warren JB. Does umbilical cord milking result in higher measures of systemic blood flow in preterm infants? Acta Paediatrica. 2017 June 20. doi:10.1111/apa.13926.

Hua N, Yieh L, Dukhovny D, Armsby L. Important considerations in the management of newborns with cyanosis. NeoReviews. 2017;18(4): e258-264.

Yieh L, Warren JB. Visual Diagnosis: Ventriculomegaly and intracranial masses. NeoReviews. 2013;14(12):e626-629.

Ng A, Uribe RA, Yieh L, Nuckels R, Gross JM. Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development. Development. 2009;136(15):2601-2611.

Research Interests: 

Healthcare economics, outcomes research, medical decision making, cost-effectiveness analysis

Current Research Studies

Cost-effectiveness of Therapeutic Hypothermia in Neonates with Mild Hypoxic Ischemic Encephalopathy

Neonatal hypoxic ischemic encephalopathy (HIE) has an incidence of 1.5 per 1000 livebirths and results in significant sequelae, including death, cerebral palsy, epilepsy, and intellectual disability. Therapeutic hypothermia is now standard of care for moderate to severe HIE as it has been shown to reduce death or disability in survivors. However, hypothermia is commonly being utilized in mild cases of HIE despite a lack of evidence of clinical efficacy. We aim to characterize the long-term neurodevelopmental outcomes of infants with mild HIE who undergo hypothermia versus those who do not while quantifying the economic burden of mild HIE over a lifetime. We will use this data to build an economic model and compare the incremental cost per quality-adjusted life year between those who undergo therapeutic hypothermia versus standard care. Findings of this analysis will aid stakeholders in understanding the economic implications and incremental benefits, if any, of inducing hypothermia in neonates with mild HIE.

PI: Dr. Yieh

Co-investigators: Dr. Hay, Dr. Wu, Dr. Lakshmanan, Dr. Friedlich, Dr. Dukhovny, Dr. Gong, Dr. Padula

Funding: K12 Pediatrician-Scientist Research Career Development Award, Children’s Hospital Los Angeles

Children's Hospital Los Angeles

4650 Sunset Blvd.
MS #31
Los Angeles, CA 90027
Phone: 323-361-5939Office
Fax: 323-361-7927Fax