Investigator, Developmental Biology and Regenerative Medicine
Assistant Professor, Research Pediatrics
  • Summary
  • Publications
  • Research

Gianluca Turcatel, PhD,  is a faculty member of the Department of Pulmonology and the Saban Research Institute. He earned his Masters of Science degree and PhD from the University of Padua in Padua, Italy. Turcatel’s research interests focus on the embryonic and postnatal lung development, adult lung injury & repair and tissue engineering. Turcatel is an assistant professor of research pediatrics with the Keck School of Medicine of the University of Southern California.

Education

Graduate School: 

PhD, University of Padua, Padua, Italy

Fellowship: 

Fellowship, Systems Biology, University of California, Irvine

Accomplishments

Professional Memberships: 

2015-present American Heart Association

2015-present Society for Developmental Biology

2017-present American Thoracic Society

2016-present European Respiratory Society

Funding

American Heart Association
Title: TGF-beta signaling pathway induces gender specific phenotype in embryonic murine lung
The Goal of this AHA Scientist development grant is to determine the role of Spock2 gene and sex hormones in the pathogensis of bronchopulmonary displasia.
Role: PD/PI

U.S. Army Medical Research Acquisition Activity
Title: Lung injury; relates to real time endoscopic monitoring of single cells’ respiratory health in lung
In this proposal, we will set up and tune a new technology that quantifies the intrinsic cellular metabolism of lung cells, which can thus be applied as a portable diagnostic tool for lung injury.
Role: Key Personnel

Publications: 

Wang P, Turcatel G, Arnesano C, Warburton D, Fraser SE, Cutrale F. Fiber pattern removal and image reconstruction method for snapshot mosaic hyperspectral endoscopic images. Biomedical Optics Express. 2018 Jan 25;9(2):780-790. doi: 10.1364/BOE.9.000780. eCollection 2018 Feb 1. PMID: 29552412

El-Hashash AH, Turcatel G, Al Alam D, Buckley S, Tokumitsu H, Bellusci S, Warburton D. Retraction: Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development doi: 10.1242/dev.058479. Development. 2017 Oct 15;144(20):3849. doi: 10.1242/dev.159673. No abstract available. PMID: 29042479

El-Hashash AHK, Turcatel G, Varma S, Berika M, Al Alam D, Warburton D. Retraction: Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium. J. Cell. Sci. doi: 10.1242/102848. Journal of Cell Science. 2017 Oct 15;130(20):3601. doi: 10.1242/jcs.211193. Epub 2017 Oct 2. No abstract available. PMID: 28972133

Turcatel G, Millette K, Thornton M, Leguizamon S, Grubbs B, Shi W, Warburton D. Cartilage rings contribute to the proper embryonic tracheal epithelial differentiation, metabolism, and expression of inflammatory genes. American Journal of Physiology, Lung Cell Mol Physiol. 2017 Feb 1;312(2):L196-L207. doi: 10.1152/ajplung.00127.2016. Epub 2016 Dec 9. PMID: 27941074

Luo Y, El Agha E, Turcatel G, Chen H, Chiu J, Warburton D, Bellusci S, Qian BP, Menke DB, Shi W. Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. BMC Biology. 2015 Jun 20;13:42. doi: 10.1186/s12915-015-0153-1. PMID: 26092405

Solari V, Borriello L, Turcatel G, Shimada H, Sposto R, Fernandez GE, Asgharzadeh S, Yates EA, Turnbull JE, DeClerck YA. MYCN-dependent expression of sulfatase-2 regulates neuroblastoma cell survival.  Cancer Research. 2014 Nov 1;74(21):5999-6009. doi: 10.1158/0008-5472.CAN-13-2513. Epub 2014 Aug 27. PMID: 25164011

Research Interests: 
  • Lung developmental biology, organogenesis, tissue injury, repair, regeneration and engineering
  • Lung idiopathic fibrosis, COPD and emphysema