Chief of Anatomic Pathology
Pediatric Pathologist
Attending Physician
  • Summary
  • Publications
  • Research
  • Locations

David M. Parham, MD is the Chief of Anatomic Pathology in the Department of Pathology and Laboratory Medicine at Children’s Hospital Los Angeles. Dr. Parham is an internationally recognized authority on the biology and diagnosis of pediatric sarcomas. He is the editor of one of the classic textbooks of pediatric pathology, Pediatric Neoplasia: Morphology and Biology and he has more recently published Concepts in Pediatric Pathology and edited Pediatric Malignancies: Pathology and Imaging. Dr. Parham is a past president of the Society for Pediatric Pathology and active member of the Children’s Oncology Group.

Education

Medical School: 

University of Tennessee Center for the Health Sciences, Memphis, Tennessee

Residency: 

University of Tennessee College of Medicine (Anatomic and Clinical Pathology)

Fellowship: 

Memorial Sloan-Kettering (Anatomic Pathology)

Accomplishments

Certification: 

American Board of Pathology - Anatomic and Clinical Pathology and Pediatric Pathology

Professional Memberships: 

United States and Canadian Academy of Pathology Member, Arthur Purdy Stout Society of Surgical Pathologists Society for Pediatric Pathology College of American Pathologists

Awards: 

Distinguished Patient Care Award, College of American Pathologists, 2011 Richard W. Leech Teaching Award, University of Oklahoma Health Sciences Center, Pathology Department, 2011 James Park Dewar, M.D., Named Professorship in Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, 2012-Present

Other Information

Publications: 

1: Rudzinski ER, Anderson JR, Hawkins DS, Skapek SX, Parham DM, Teot LA. The World Health Organization Classification of Skeletal Muscle Tumors in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group. Arch Pathol Lab Med. 2015 May 19. [Epub ahead of print] PubMed PMID: 25989287.

2: Zhou S, Parham DM, Yung E, Pattengale P, Wang L. Quantification of Glypican 3, Beta-catenin and Claudin-1 Protein Expression in Hepatoblastoma and Pediatric Hepatocellular Carcinoma by Color Deconvolution. Histopathology. 2015 May 4. doi:10.1111/his.12730. [Epub ahead of print] PubMed PMID: 25939253.

3: VandenHeuvel KA, Carpentieri DF, Chen J, Fung KM, Parham DM. Ectomesenchymoma with embryonal rhabdomyosarcoma and ganglioneuroma, arising in association with benign triton tumor of the tongue. Pediatr Dev Pathol. 2014 May-Jun;17(3):226-30. doi: 10.2350/14-01-1433-CR.1. Epub 2014 Mar 20. PubMed PMID: 24650353.

4: Rudzinski ER, Anderson JR, Lyden ER, Bridge JA, Barr FG, Gastier-Foster M, Bachmyer K, Skapek SX, Hawkins DS, Teot LA, Parham DM. Myogenin, AP2β, NOS-1, and HMGA2 are surrogate markers of fusion status in rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group. Am J Surg Pathol. 2014 May;38(5):654-9. doi: 10.1097/PAS.0000000000000195. PubMed PMID: 24618610; PubMed Central PMCID: PMC4010390.

5: Parham DM, Barr FG. Classification of rhabdomyosarcoma and its molecular basis. Adv Anat Pathol. 2013 Nov;20(6):387-97. doi: 10.1097/PAP.0b013e3182a92d0d. Review. PubMed PMID: 24113309.

Research Interests: 

Pediatric neoplasms: correlation of morphology and biologic features Pediatric sarcomas: classification and grading Unusual pediatric infections association with immunosuppression Research in Progress: International classification of rhabdomyosarcomas Childhood sarcomas: long-term outcome, grading, and pathology study, Children’s Oncology Group High-risk rhabdomyosarcoma, ARST08P1, Children’s Oncology Group Review of pediatric soft tissue sarcomas entered in Children’s Oncology Group Banking Protocol

4650 Sunset Blvd.
MS #43
Los Angeles, CA 90027
Phone: 323-361-5303Office
Fax: 323-361-8005Fax