Research Seminar: "Anesthetic Neurotoxicity in Pediatrics"
Presented by
Mary Ellen McCann, MD, MpH
Associate Professor of Anesthesia
Harvard Medical School and Senior Associate in Anesthesia
Boston Children's Hospital
Talk Summary
The focus of this talk is to briefly review the evidence of anesthetic neurotoxicity in young animals and discuss a few possible mechanisms. Then, I will discuss briefly the available clinical evidence of anesthesia induced neurotoxicity in humans and the findings of the GAS trial. Finally, I discuss other important anesthetic management techniques such as maintaining blood pressure, normocapnia, normoxia, euglycemia, normothermia and neutral positioning to improve the neurocognitive outcomes of at-risk children.
About the Speaker
The focus of my research is the safety of general anesthesia and sedatives with regard to neurodevelopmental outcomes of human infants and toddlers. As a clinical pediatric anesthesiologist with extensive contacts within the pediatric anesthesia community, I designed and implemented a multinational, prospective, randomized trial of general anesthesia toxicity in very young infants known as the GAS trial. I am also very interested in outcomes research in childhood and adolescent scoliosis surgery. I am also a member of the Joint Committee on the Status of Women at Harvard Medical School and started the Subcommittee on Flexible Work Pathways.
Hosted by
Barry Markovitz, MD, MPH
Chair, Anesthesiology Critical Care Medicine
Children's Hospital Los Angeles
Professor of Clinical Pediatrics and Anesthesiology
USC Keck School of Medicine
Additional Information
Lunch will be provided to seminar guests; first come, first served
Help us save plastic! Bring your own water bottles. Water will be available to fill your bottles.
Brought to you by TSRI Office of Training, Education, Career Planning & Development (TECPAD)
RSVP is required to tecpad@chla.usc.edu