Research Blog

Published on May 13, 2016
While human genome studies can lead to medical breakthroughs in the diagnosis and treatment of various conditions, the subject of genome research can also aggravate sensitivities. And while the knowledge that some health problems are more prevalent among certain populations has... Read More
Published on May 9, 2016
From skin rashes and hives to difficulty breathing and more serious reactions, food allergies affect up to six million children in the United States alone. But over the last two decades, researchers have discovered it can also lead to another condition known as eosinophilic... Read More
Published on May 5, 2016
“Natural killer" cell (green) attacks a leukemia cell (red). Courtesy of Eleanora Heisterkamp,PhD, Jihane Khalife, and Esteban Fernandez, PhD.Researchers at Children’s Hospital Los Angeles have shown that a select team of immune-system cells from leukemia patients can be... Read More
Published on May 3, 2016
Inadequate lung development can lead to a variety of pediatric disorders, especially in babies born prematurely. Understanding what drives proper lung development is important to developing new therapies for children with these disorders, but researching this can be complicated... Read More
Published on April 28, 2016
Evidence-based research proves they can with early educationA field trip to the local Ralph’s was a first for the Wiz Kids Preschool in Culver City, CA.  Thirty preschoolers between the ages of 3 and 5 were marched down Overland Avenue to shop for healthy food items from the... Read More
Published on April 25, 2016
In 2009, the Nobel Prize in Medicine was awarded for the discovery of telomerase, a previously little known protein that plays a key role in preventing damage to chromosomal DNA.“One of the recipients of the Nobel Prize, Dr. Elizabeth Blackburn, reminded us then that we are all... Read More
Published on April 21, 2016
Probiotics, bacteria believed to be beneficial for health, are thought to help with various gastrointestinal issues. A recent nationwide study published in the American Journal of Infection Control found it is common for hospitals to prescribe probiotics to patients with a... Read More
Published on April 19, 2016
Cultured retinoblastoma tumor containing tumor cells (red) and fibroblasts (green).  Researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) have demonstrated that targeting survivin – a protein that inhibits apoptosis or cell death – enhances the... Read More
Published on April 17, 2016
When Bacteria Invade…Despite therapeutic advances, mortality rates for neonatal meningitis have remained the same over the last two decades. Addressing this requires better understanding of how the disease is caused at a cellular and molecular level. Here we see the re-... Read More
Published on April 13, 2016
A staple of pediatric  healthcare, antibiotics are the most prescribed medication for children. However, the long-term effects of these medications remain relatively unknown. Last month, two studies looked into the links between antibiotic use and childhood obesity, finding... Read More
Published on April 8, 2016
Shedding epithelial cells in the intestine. Image courtesy of Mark R. Frey, PhD, The Saban Research Institute, Children’s Hospital Los Angeles.The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a... Read More
Published on April 6, 2016
Children’s Hospital Los Angeles to Initiate Clinical Trial for Kids with Treatment-Resistant LeukemiaResearchers at Children’s Hospital Los Angeles will be testing a new therapy for acute lymphoblastic leukemia using specially engineered T-cells isolated from patients that can... Read More
Published on April 4, 2016
In a new editorial published in JAMA Pediatrics, Johanna Olson-Kennedy, MD, medical director of The Center for Transyouth Health and Development at Children’s Hospital Los Angeles discusses disparities in mental health in young transgender populations. A recent study, also... Read More
Published on March 31, 2016
Here we see the development of the brain-pancreas axis during gestation. According to a new study out of Children’s Hospital Los Angeles, the hormone leptin alters neuronal growth between the brain and pancreas during embryonic development, which may play a role in the onset... Read More
Published on March 29, 2016
Eczema or atopic dermatitis is a condition where the areas of the skin are inflamed, resulting in symptoms ranging from redness to severe rashes and blisters. The specific causes of eczema remain unknown, though the condition has been linked to other conditions ranging from... Read More
Published on March 24, 2016
Children’s Hospital Los Angeles Awarded $7.1 Million by CIRM to develop new cellular therapy to treat digestive nerve disordersHirschsprung’s disease, where crucial nerve cells are absent in parts of the gastrointestinal tract resulting in the inability to properly push food... Read More
Published on March 23, 2016
The scientific and healthcare communities have become increasingly aware of the profound impact that early life events have on the lifelong health and well-being of children and the adults they will become.
Published on March 22, 2016
A new study out of Children’s Hospital Los Angeles has found excessive fat in legs of children with a severe form of spina bifida suggests increased risk for metabolic disordersRepresentative quantified computed tomography (CT) slices showing excess adipose or fatty tissues (... Read More
Published on March 18, 2016
Despite Increases in Screening, Study Finds Only 44 Percent of Pediatricians Inquire about Maternal DepressionMaternal depression affects up to 40 percent of mothers with young children and can have many negative effects on the infant and developing child including feeding... Read More
Published on March 16, 2016
We are living through a revolution in biology that is giving us a deeper, sharper understanding about how early experience effects development of the brain.