Research Blog

Published on March 8, 2019
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They wear lab coats in place of capes, safety goggles instead of masks, and wield pipets - not swords. But they are still our heroes.At CHLA, we are proud to honor women in science for International Women’s Day!Please visit www.chla.org/womeninscience to learn about 6 talented... Read More
Published on March 1, 2019
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When blood flow is blocked in the brain, a small portion of brain tissue starves and dies – this is known as a stroke. By the time a patient with Sickle Cell Disease (SCD) is 30 years old, he or she has a 50% chance of having a stroke. Children’s Hospital Los Angeles physician... Read More
Published on February 14, 2019
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How a fish smaller than a pinky finger holds big clues to saving heartsWhat do zebrafish and newborn babies have in common? Both are small, yet hold vast potential for the future. But these two organisms are more intertwined than you might think.Ching-Ling (Ellen) Lien, PhD, of... Read More
Published on February 11, 2019
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Scientists pinpoint a set of genes that may wire the body weight center of the brainEating and exercise have the power to shape our bodies but those activities are controlled by hard-wired circuits in the brain. This means that when these neural circuits are developing is a... Read More
Published on February 7, 2019
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With autism diagnoses on the rise, science is on the hunt for answers. New research at Children’s Hospital Los Angeles uses advanced imaging techniques to uncover some clues.Each year, one in 59 children are diagnosed with Autism Spectrum Disorder (ASD), a condition that impacts... Read More
Published on February 4, 2019
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Bayanihan is a Filipino term that means working together in the community to accomplish a difficult task. It is a generation ago. A young girl named Joyce was born in Historic Filipinotown, Los Angeles – where many immigrants from the Philippines often first settle. Her... Read More
Published on January 9, 2019
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CHLA’s Dr. Bradley Peterson weighs in on what it takes to develop a human brain In a public town-hall style event, CHLA’s Dr. Bradley Peterson spoke amongst a panel of early childhood specialists. The event was organized by KPCC In Person and hosted by Priska Neely, who covers... Read More
Published on January 2, 2019
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Cell phones are small but mighty. They’re essentially fully functional computers that fit in our back pockets. But if our phone stops working, we don’t know how to fix it ourselves – we take it to a specialist. Luckily, there is a standardized template for how it is... Read More
Published on December 20, 2018
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Actually, it can hide. CHLA’s Yong-Mi Kim tells us exactly how leukemia burrows within bone marrow, where it is shielded from cancer treatments. But given Kim’s breakthrough research on acute lymphoblastic leukemia, it won’t be able to hide forever.Acute lymphoblastic leukemia (... Read More
Published on December 6, 2018
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FDA grants accelerated approval for Vitrakvi® (larotrectinib) for the treatment of solid tumors. This is the second FDA-approved drug for cancers based on their genetic makeup as opposed to location in the body.While other toddlers her age were fighting naptime, two-year-old... Read More
Published on March 28, 2018
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1 out of 68 children in the United States will be diagnosed with an Autism Spectrum Disorder (ASD). The prevalence of an ASD diagnosis grew by 72 percent between 2007 and 2011. Tech-based interventions targeted to children with autism have the potential to help solve challenges... Read More
Published on March 12, 2018
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The sidewalk was smooth and the sky was clear, so Sophia Cabrera took out her skateboard and went for a ride. Before she could return home, she fell, landed in a heap and broke her arm. Funny thing is, she and her family couldn’t have been happier. Falls and fractures are... Read More
Published on March 8, 2018
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(Left to Right) Douglas Nordli, Jr., MD, CHLA Chief of Pediatric Neurology; Robert E. Shaddy, MD, CHLA Pediatrician-in-Chief; Rohit Kohli, MBBS, MS, CHLA Chief of Gastroenterology, Hepatology, and Nutrition. This year, three physician researchers at Children’s Hospital Los... Read More
Published on March 5, 2018
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Baby Jasmine was born in late December with hypoplastic left heart syndrome (HLHS) and had her first open-heart surgery at five days old. She is enrolled in the groundbreaking clinical trial at Children’s Hospital Los Angeles. New therapy could boost organ... Read More
Published on November 28, 2017
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David Warburton, MD, has been elected a 2017 Fellow of the American Association for the Advancement of Science (AAAS) in recognition his contributions to innovation, education, and scientific leadership in the Section of Medical Sciences.  Warburton, who is the director of the... Read More
Published on November 14, 2017
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A protein lining the inner layer of the heart. The protein is required for heart muscles to proliferate during development.Ram Kumar Subramanyan, MD, PhD, brings a unique point of view to the laboratory, where his goal is to one day use stem cells to create replacement parts for... Read More
Published on November 7, 2017
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The Sharon D. Lund Foundation has awarded $400,000 to Michele Kipke, PhD, vice chair of Research and division head of Research on Children, Youth and Families. The funding will support research efforts of the Boone Fetter Clinic and the Institute for the Developing Mind to... Read More
Published on October 10, 2017
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Investigators identify pathway that causes immune cells to support cancer, instead of killing itInvestigators at the Children’s Center for Cancer and Blood Diseases at Children’s Hospital Los Angeles have identified new findings about an immune cell – called a tumor-... Read More
Published on October 6, 2017
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New Biomarker Assay Detects Neuroblastoma with Greater Sensitivity Investigators at The Saban Research Institute of Children’s Hospital Los Angeles have developed and tested a new biomarker assay for quantifying disease and detecting the presence of neuroblastoma even when... Read More
Published on September 19, 2017
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The event, which was open to CHLA’s clinical research personnel, postdocs, students, faculty and other staff, brought together twenty-five unique resource representatives from CHLA and the Southern California Clinical and Translational Science Institute (SC CTSI... Read More

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