Research Blog

Published on July 15, 2016
Robert Seeger, MD (center), in 1991Cell lines, or populations of identical cells maintained in a laboratory, are fundamental to even the most basic of biomedical research. With a thriving cell line, researchers do not have to rely on precious, and often rare, patient samples.“... Read More
Published on July 12, 2016
While rare, a percentage of congenital craniofacial abnormalities may indicate a risk of developing cancer. This critical insight may change the course of treatment in order to ensure the best possible outcome for patients.Seemingly straightforward craniofacial conditions, such... Read More
Published on July 8, 2016
What happens in early childhood can matter for a lifetime.Pediatricians are growing increasingly alarmed about the dangers of so-called “toxic stress”—chronic activation of a young child’s stress response systems due to repeated, uncontrollable adverse events, which can alter... Read More
Published on July 5, 2016
Sudden Infant Death Syndrome (SIDS), the unexplained sudden death of an infant under the age of one year, affects approximately 1500 infants annually. Its exact cause remains a mystery, but a recent study in Pediatrics has revealed a possible risk factor. Researchers have found... Read More
Published on July 1, 2016
One family’s health scare leads to new hope for children with brain and spinal cord tumorsErika Kort had just finished dance class when her legs started to feel numb. Thinking she probably just pulled a muscle, the 16-year-old wasn’t concerned until the sensation began spreading... Read More
Published on June 28, 2016
Many clinicians don’t feel confident about treating kids with autism and related mental health disorders, which may come as no surprise to parents of children with autism spectrum disorders (ASD). Up to 70% of children with ASD have a co-occurring mental health disorder such as... Read More
Published on June 24, 2016
How kids’ intuitive use of technology advances care at Children’s Hospital Los AngelesSometimes it seems like today’s kids were born with a cell phone in hand, intuitively searching the Web and sharing selfies on Instagram. These “digital natives” have been immersed in... Read More
Published on June 22, 2016
Researchers at The Saban Research Institute of Children’s Hospital Los Angeles have identified a new genetic candidate for testing therapies that might affect fear learning in people with PTSD or other conditions. Results of the study have been published in the Journal of... Read More
Published on June 21, 2016
Neurons in the hypothalamus develop abnormally in Prader-Willi Syndrome A study published in the journal Human Molecular Genetics by researchers at Children’s Hospital Los Angeles (CHLA) provides novel insights into the brain mechanisms underlying the... Read More
Published on June 17, 2016
Bench to Bassinet research into congenital heart disease at CHLACardiothoracic surgeon Richard Kim, MD, is interested in doing more than basic research alone. “I want to do research that has a real impact on our patients,” he says, “with results that I can see in my lifetime.”... Read More
Published on June 15, 2016
Tracy C. Grikscheit, MD, pediatric surgeon and principal investigator at The Saban Research Institute of Children’s Hospital Los Angeles, treats a large number of young patients who require surgery for various intestinal diseases.  Since the intestinal microbiome is an important... Read More
Published on June 14, 2016
Pediatric residents prepare for the next big earthquakeWhile experts agree that the West Coast is due for a sizable earthquake, there is little consensus as to when such an event may hit. Therefore, preparation will be a key component to survival and good outcomes for major... Read More
Published on June 10, 2016
E.coli K1 infection of the hippocampus, the center of cognitive function in the brain. Image courtesy of Alexander Chang, PhD, The Saban Research Institute, Children’s Hospital Los Angeles.Despite effective antibiotic treatments for bacterial meningitis, half of survivors suffer... Read More
Published on June 8, 2016
Screening of thousands of children in California suggests which mutations are disease-causing and which are benignWhen it comes to cystic fibrosis (CF), more than 2,000 different genetic mutations have been reported.  However, only 200 of them have been categorized – leaving a... Read More
Published on June 3, 2016
Optimizing Adult Treatments for Pediatric Patients with Glaucoma and Cataracts “My goal is to decrease childhood blindness by treating pediatric eye disease in an innovative way,” says Bibiana Jin Reiser, MD, MS, director of the Cornea and Glaucoma Institute at The Vision Center... Read More
Published on May 30, 2016
Children’s Hospital Los Angeles awarded two summer fellowships through the St. Baldrick’s Foundation for pediatric cancer researchIn 2013, less than 4 percent of research funding from the National Cancer Institute went to research for pediatric cancers, the leading cause of... Read More
Published on May 27, 2016
CHLA Physician Todd Chang is using serious gaming as a tool to train young doctors Activity in the emergency department (ED) in a pediatric hospital is fast-paced, and the most precious resource is time. With more than 80,000 patients to attend to every year for trauma, rare... Read More
Published on May 25, 2016
The California Institute for Regenerative Medicine awards grant to CHLA researcher for CRISPR/Cas9 project to treat genetic diabetesOften touted as one of the most revolutionary biomedical technologies of the modern age, the CRISPR/Cas9 gene editing system has already led to new... Read More
Published on May 19, 2016
Carotid artery thickness is fueled by androgen hormones in cases of classical adrenal hyperplasia according to a new research study out of Children’s Hospital Los Angeles. This finding has significant implications for preventing cardiovascular disease in young adults. Youth with... Read More
Published on May 17, 2016
From the Eat 5 a Day initiative to increase fruit and vegetable consumption to First Lady Michelle Obama’s Let’s Move campaign, many efforts have been made to curb the growing incidence of childhood obesity. But a troubling new study suggests a lot more work needs to be done.... Read More