Research Blog
Published on May 16, 2019
Research performed over the last several decades has led to
an increased understanding of the genetics of cancer. The clinical application
of this knowledge for pediatric cancer has lagged behind studies performed for
adults. In a perspectives article published in the... Read More
Published on May 16, 2019
For the tenth year in a row, doctors, family members, and the Los
Angeles community came together to support cancer research at the St.
Baldrick’s Annual Head Shave Event. This year’s event held particular
significance for one of CHLA’s doctors, Robert Seeger, MD, MS (pictured... Read More
Published on April 9, 2019
Bringing a baby into the world involves many firsts – mothers
and fathers are discovering their new roles, babies are learning what it means
to live outside the womb, and the family is forging a relationship and bonding.
But what happens when this time of uncertainty is... Read More
Published on March 19, 2019
A
cancer gene called MYCN (red) appears in high levels in cone cells (green). These
cone cells can go on to form retinoblastoma tumors. Image provided by Dr. Hardeep Singh, Children’s Hospital Los
Angeles.Retinoblastoma is a tumor of the retina that generally affects... Read More
Published on March 8, 2019
They wear lab coats in place of capes, safety goggles instead of masks, and wield pipets - not swords. But they are still our heroes.At CHLA, we are proud to honor women in science for International Women’s Day!Please visit www.chla.org/womeninscience to learn about 6 talented... Read More
Published on March 1, 2019
When blood flow is blocked in the brain, a small portion of
brain tissue starves and dies – this is known as a stroke. By the time a
patient with Sickle Cell Disease (SCD) is 30 years old, he or she has a 50%
chance of having a stroke. Children’s Hospital Los Angeles physician... Read More
Published on February 14, 2019
How a fish smaller than a pinky finger holds big clues to saving heartsWhat do zebrafish and newborn babies have in common? Both
are small, yet hold vast potential for the future. But these two organisms are
more intertwined than you might think.Ching-Ling
(Ellen) Lien, PhD, of... Read More
Published on February 11, 2019
Scientists pinpoint a set of genes that may wire the body weight center
of the brainEating and exercise have the
power to shape our bodies but those activities are controlled by hard-wired
circuits in the brain. This means that when these neural circuits are
developing is a... Read More
Published on February 7, 2019
With autism diagnoses
on the rise, science is on the hunt for answers. New research at Children’s
Hospital Los Angeles uses advanced imaging techniques to uncover some clues.Each year, one in 59 children are diagnosed with Autism
Spectrum Disorder (ASD), a condition that impacts... Read More
Published on February 4, 2019
Bayanihan is a Filipino term that means working together in the community to accomplish a difficult task.
It is a generation ago. A young girl named Joyce was born in
Historic Filipinotown, Los Angeles – where many immigrants from the Philippines
often first settle. Her... Read More
Published on January 9, 2019
CHLA’s Dr. Bradley
Peterson weighs in on what it takes to develop a human brain In a public town-hall style event, CHLA’s Dr. Bradley Peterson
spoke amongst a panel of early childhood specialists. The event was organized
by KPCC In Person and hosted by Priska
Neely, who covers... Read More
Published on January 2, 2019
Cell phones are small but mighty. They’re essentially fully functional
computers that fit in our back pockets. But if our phone stops working, we don’t
know how to fix it ourselves – we take it to a specialist. Luckily, there is a
standardized template for how it is... Read More
Published on December 20, 2018
Actually, it can
hide. CHLA’s Yong-Mi Kim tells us exactly how leukemia burrows within bone
marrow, where it is shielded from cancer treatments. But given Kim’s
breakthrough research on acute lymphoblastic leukemia, it won’t be able to hide
forever.Acute lymphoblastic leukemia (... Read More
Published on December 6, 2018
FDA grants accelerated
approval for Vitrakvi® (larotrectinib) for the treatment of solid tumors. This
is the second FDA-approved drug for cancers based on their genetic makeup
as opposed to location in the body.While other toddlers her age were fighting naptime,
two-year-old... Read More
Published on March 28, 2018
1 out of 68
children in the United States will be diagnosed with an Autism Spectrum
Disorder (ASD). The prevalence of an ASD diagnosis grew by 72 percent between
2007 and 2011. Tech-based interventions targeted to children with autism have
the potential to help solve challenges... Read More
Published on March 12, 2018
The
sidewalk was smooth and the sky was clear, so Sophia Cabrera took out her
skateboard and went for a ride. Before she could return home, she fell, landed
in a heap and broke her arm. Funny thing is, she and her family couldn’t have
been happier. Falls and fractures are... Read More
Published on March 8, 2018
(Left to Right)
Douglas Nordli, Jr., MD, CHLA Chief of Pediatric Neurology; Robert E. Shaddy,
MD, CHLA Pediatrician-in-Chief; Rohit Kohli, MBBS, MS, CHLA Chief of
Gastroenterology, Hepatology, and Nutrition. This year, three physician
researchers at Children’s Hospital Los... Read More
Published on March 5, 2018
Baby Jasmine was born in late December with
hypoplastic left heart syndrome (HLHS) and had her first open-heart surgery at
five days old. She is enrolled in the groundbreaking clinical trial at
Children’s Hospital Los Angeles. New
therapy could boost organ... Read More
Published on November 28, 2017
David Warburton, MD, has been
elected a 2017 Fellow of the American Association for the Advancement of
Science (AAAS) in recognition his contributions to innovation, education, and
scientific leadership in the Section of Medical Sciences. Warburton, who is the director of the... Read More
Published on November 14, 2017
A protein lining the inner layer of the heart. The protein is required for heart muscles
to proliferate during development.Ram Kumar
Subramanyan, MD, PhD, brings a unique point of view to the laboratory,
where his goal is to one day use stem cells to create replacement parts for... Read More