Research Blog

Published on June 29, 2015
Many hospitals lack the resources and patient volume to employ a round-the-clock, neonatal intensive care specialist to treat their youngest and sickest patients. Telemedicine—with real-time audio and video communication between a neonatal intensive care specialist and a patient... Read More
Published on June 26, 2015
After 13 years at Columbia University, Bradley S. Peterson, MD, joined CHLA last year as the inaugural director of the Institute for the Developing Mind (IDM) at The Saban Research Institute.In the latest issue of ResearCHLA Magazine, Dr. Peterson discusses how the IDM will... Read More
Published on June 24, 2015
Patients don’t fail therapy. But sometimes, therapy fails them. Read More
Published on June 19, 2015
Investigators at Children’s Hospital Los Angeles are providing new hope for babies with short bowel syndrome (SBS) by developing a novel model of SBS in zebrafish, described in a paper published online on June 18 by the American Journal of Physiology-Gastrointestinal and Liver... Read More
Published on June 18, 2015
Researchers at Children’s Hospital Los Angeles have demonstrated that adolescents and young adults with congenital adrenal hyperplasia (CAH) have significantly increased amounts of abdominal fat tissue, placing them at greater risk for harmful conditions linked to obesity,... Read More
Published on June 17, 2015
To help understand this paper, I had to draw a picture! Feel free to use as a reference.In a finding that furthers our understanding of human immunodeficiency virus (HIV), researchers from Children’s Hospital Los Angeles discovered two locations where a single difference in HIV’... Read More
Published on June 2, 2015
Facing the bleakest odds, Andreas Reiff, MD, helped launch a new age in the treatment of autoimmune disease.  During his fellowship, Reiff and others at CHLA helped discover the inflammatory signaling pathways of a substance called tumor necrosis factor (TNF); excess levels of... Read More
Published on May 24, 2015
At the 3rd Light Up the Blues Concert, emcee Jack Black introduced Pat Levitt, PhD, Simms/Mann Chair in Developmental Neurogenetics at Children’s Hospital Los Angeles. Dr. Levitt asked the audience, “How many of you have had, at least once in your life, really challenging... Read More
Published on May 19, 2015
A recent study—published online in the journal of Cancer Research on April 23—demonstrates that a growth factor called G-CSF, commonly used in high-risk neuroblastoma treatment, leads to increased tumor growth and metastasis by stimulating cancer stem cells in an experimental... Read More
Published on May 19, 2015
Physicians use a growing array of diagnostic imaging equipment, such MR, CT, ultrasound and X-rays.  Due to the massive size of the digital files, remote sharing of these medical images with patients or other clinicians has been very difficult. Patients have had to ask their... Read More
Published on May 14, 2015
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and includes two subtypes, B-cell and T-cell, depending upon the type of white blood cell where the leukemia originates. For B-cell ALL, the presence of a small number of remaining leukemia cells, called... Read More
Published on May 13, 2015
Researchers at Children’s Hospital Los Angeles have made an important step toward finding a target in the fight against drug-resistant neuroblastoma (NBL), the most common solid malignancy found, outside of the skull, in children.  Led by Muller Fabbri, MD, PhD, of the Children’... Read More
Published on May 4, 2015
“Bays of Our Lives” is a series that goes behind the laboratory bench (also called a “bay”) to highlight the individual personalities behind innovative research at Children’s Hospital Los Angeles (CHLA). Sunhye Lee, PhD, is a new postdoctoral student studying... Read More
Published on May 1, 2015
Long term, these options are still not good enough. When we think about treating children, we need a solution that will last a lifetime Read More
Published on April 29, 2015
Acupuncture isn’t just for chronic pain—it turns out that this ancient needling technique may also have a role in managing acute pain in the emergency department. Researchers from Children’s Hospital Los Angeles recently examined the effects of acupuncture treatment on pain and... Read More
Published on April 27, 2015
Model of coagulation factor VIII. Credit: ShutterstockChildren with hemophilia A require three to four infusions each week to prevent bleeding episodes, chronic pain and joint damage. The effect on quality of life can be significant, due to time and discomfort associated with... Read More
Published on April 24, 2015
Johanna Olson, MD, is a pediatrician specializing in adolescent medicine at Children’s Hospital Los Angeles, where she directs the Center for Transyouth Health and Development. Olson was recently featured on “Bruce Jenner–The Interview” with Diane Sawyer on ABC.Transgender... Read More
Published on April 22, 2015
Medulloblastoma (glowing white) in 15-year-old boy. Image contributed to Radiopaedia by Paresh K. Desai, MD.Located in the cerebellum, medulloblastoma is one of the most common cancerous brain tumors in children and can cause behavioral changes, nausea, vomiting and decreases in... Read More
Published on April 15, 2015
Delving into what she calls “survivor biology,” Barbara Driscoll explores how early childhood ailments can affect future health.Long after the aches and pains disappear, our bodies still remember the impact of illness. Barbara Driscoll, PhD, explores how cells use their first... Read More
Published on April 13, 2015
Immunofluorescence staining of cultured cells from a child’s retinoblastoma tumor. 10x magnification. Image courtesy of Narine Harutyunyan, Jennifer Aparicio, PhD, and Thomas Lee, MD, The CHLA Vision Center LaboratoryAfter surgical removal, retinoblastoma tumors make their... Read More