Research Blog

Published on May 19, 2015
Physicians use a growing array of diagnostic imaging equipment, such MR, CT, ultrasound and X-rays.  Due to the massive size of the digital files, remote sharing of these medical images with patients or other clinicians has been very difficult. Patients have had to ask their... Read More
Published on May 14, 2015
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and includes two subtypes, B-cell and T-cell, depending upon the type of white blood cell where the leukemia originates. For B-cell ALL, the presence of a small number of remaining leukemia cells, called... Read More
Published on May 13, 2015
Researchers at Children’s Hospital Los Angeles have made an important step toward finding a target in the fight against drug-resistant neuroblastoma (NBL), the most common solid malignancy found, outside of the skull, in children.  Led by Muller Fabbri, MD, PhD, of the Children’... Read More
Published on May 4, 2015
“Bays of Our Lives” is a series that goes behind the laboratory bench (also called a “bay”) to highlight the individual personalities behind innovative research at Children’s Hospital Los Angeles (CHLA). Sunhye Lee, PhD, is a new postdoctoral student studying... Read More
Published on May 1, 2015
Long term, these options are still not good enough. When we think about treating children, we need a solution that will last a lifetime Read More
Published on April 29, 2015
Acupuncture isn’t just for chronic pain—it turns out that this ancient needling technique may also have a role in managing acute pain in the emergency department. Researchers from Children’s Hospital Los Angeles recently examined the effects of acupuncture treatment on pain and... Read More
Published on April 27, 2015
Model of coagulation factor VIII. Credit: ShutterstockChildren with hemophilia A require three to four infusions each week to prevent bleeding episodes, chronic pain and joint damage. The effect on quality of life can be significant, due to time and discomfort associated with... Read More
Published on April 24, 2015
Johanna Olson, MD, is a pediatrician specializing in adolescent medicine at Children’s Hospital Los Angeles, where she directs the Center for Transyouth Health and Development. Olson was recently featured on “Bruce Jenner–The Interview” with Diane Sawyer on ABC.Transgender... Read More
Published on April 22, 2015
Medulloblastoma (glowing white) in 15-year-old boy. Image contributed to Radiopaedia by Paresh K. Desai, MD.Located in the cerebellum, medulloblastoma is one of the most common cancerous brain tumors in children and can cause behavioral changes, nausea, vomiting and decreases in... Read More
Published on April 17, 2015
Not every patient with hemophilia is going to bleed the same way, and not every patient is going to respond the same way to the treatments we give. Going forward, we hope to use this technology to individualize patient care. Read More
Published on April 15, 2015
Delving into what she calls “survivor biology,” Barbara Driscoll explores how early childhood ailments can affect future health.Long after the aches and pains disappear, our bodies still remember the impact of illness. Barbara Driscoll, PhD, explores how cells use their first... Read More
Published on April 13, 2015
Immunofluorescence staining of cultured cells from a child’s retinoblastoma tumor. 10x magnification. Image courtesy of Narine Harutyunyan, Jennifer Aparicio, PhD, and Thomas Lee, MD, The CHLA Vision Center LaboratoryAfter surgical removal, retinoblastoma tumors make their... Read More
Published on April 9, 2015
Pointillism artwork can be seen on museum walls and under the microscope. Left: Stem cells stained with DAPI blue, The Saban Research Institute of Children’s Hospital Los AngelesRight: Study for “The Channel at Gravelines, Evening,” Georges Seurat (1890). Musée de l'Annonciade,... Read More
Published on April 7, 2015
Since 2000, the rate of infants born with an addiction to narcotics or other drugs has tripled in the U.S. Dr. Friedlich and Claire McLean, MD, address this growing issue on First 5 LA:“If substances of abuse exist, pregnant women will use them just like anyone else and my... Read More
Published on April 2, 2015
In a condition as heterogeneous as autism spectrum disorder(ASD), finding a shared root of behavioral and neurological symptoms is often a shot in the dark. But in the mid-2000s, researchers found a genetic mutation in one percent of children with ASD, making it the most common... Read More
Published on March 31, 2015
In the fall of last year, a severe respiratory illness crept across the country, causing a string of infections in children. While most of those affected—even those that were hospitalized—recovered fully, a handful of kids with the enterovirusD68 (EV-D68) infection experienced... Read More
Published on March 30, 2015
Characterizing associations between socioeconomic factors and children’s brain development, a team of investigators from nine universities across the country reports correlative links between family income and brain structure. Relationships between the brain and family income... Read More
Published on March 27, 2015
Caption: Comparative sizes of fetal and adult pacemakers. Credit: Children’s Hospital Los AngelesA team of investigators at Children’s Hospital Los Angeles and the University of Southern California have developed the first fully implantable micropacemaker designed for use in a... Read More
Published on March 25, 2015
Prenatal Exposure to Common Air Pollutants Linked to Cognitive and Behavioral ImpairmentEveryday pollutants in and outside the home can be bad for the environment…and bad for your baby’s brainResearchers at the Institute for the Developing Mind at Children’s Hospital Los Angeles... Read More
Published on March 18, 2015
Caption: Transgenic mouse model used to target lung mesenchymal cells (green). Credit: Wei Shi, MD, PhD, Developmental Biology and Regenerative Medicine Research Program at Children’s Hospital Los Angeles___________________________________________________By uncovering the... Read More