Research Blog

Published on July 29, 2015
Difference aids in childbearing, but likely imparts a greater susceptibility for scoliosis and osteoporosis in females Looking at measurements of the vertebrae – the series of small bones that make up the spinal column – in newborn children, investigators at Children’s... Read More
Published on July 27, 2015
According to a recent article in The New York Times, a study published in the journal Circulation found that consumption of sugary drinks results in some 184,000 deaths worldwide each year. The study’s researchers further estimate that sweetened drinks cause 133,000 deaths from... Read More
Published on July 24, 2015
Researchers in the Division of Hematology, Oncology and Blood & Marrow Transplantation at Children’s Hospital Los Angeles have shown greatly improved outcomes in using stem cell transplantation to treat patients with a serious but very rare form of chronic blood cancer... Read More
Published on July 22, 2015
Johanna Olson, MD, and her colleagues at Children’s Hospital Los Angeles, provide care for the largest number of transyouth in the U.S. and have enrolled 101 patients in a study to determine the safety and efficacy of treatment that helps patients bring their bodies into closer... Read More
Published on July 20, 2015
Idiopathic pulmonary fibrosis (IPF) is a progressively lethal lung disease, with few effective treatment options.  Researchers at The Saban Research Institute of Children’s Hospital Los Angeles have found that a biomarker commonly associated with cell injury called Annexin V may... Read More
Published on July 17, 2015
124352240944_0.png colitis flares, there is an inflammatory process that kills both bacteria and colon cells mistakenly identified as pathogenic. The body mounts a counterforce, seeking to repair the intestinal lining.... Read More
Published on July 15, 2015
Researchers at Children’s Hospital Los Angeles and the University of Southern California found that children with autism spectrum disorder, as well as typically developing children, experience less stress in a sensory-adapted environment than in a regular dental clinic.A trip to... Read More
Published on July 13, 2015
This video is a fly-through of the colon. Much of the lining has been destroyed by a severe bout of colitis. Each frame depicts a progressively deeper layer of the colon with stem cells (shown in red) working to repair the organ.Image: mouse colonVideo credit: Cambrian Liu, PhD... Read More
Published on July 10, 2015
Retinoblastoma (or RB) is a childhood retinal tumor usually affecting children 1 to 2 years of age. Although rare, it is the most common malignant tumor of the eye in children.A common sign of this cancer is a white glow or glint in the pupil of one or both eyes. Parents may... Read More
Published on July 8, 2015
Two minutes, Frank Ing, MD, tells a visitor, with all the best intentions. He flashes a pair of fingers as reinforcement. “Two minutes.”Then he’s off on what he might call a mission of eminence, seeing Children’s Hospital Los Angeles through the final moments of a year-long... Read More
Published on July 6, 2015
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Published on June 29, 2015
Many hospitals lack the resources and patient volume to employ a round-the-clock, neonatal intensive care specialist to treat their youngest and sickest patients. Telemedicine—with real-time audio and video communication between a neonatal intensive care specialist and a patient... Read More
Published on June 26, 2015
After 13 years at Columbia University, Bradley S. Peterson, MD, joined CHLA last year as the inaugural director of the Institute for the Developing Mind (IDM) at The Saban Research Institute.In the latest issue of ResearCHLA Magazine, Dr. Peterson discusses how the IDM will... Read More
Published on June 24, 2015
Patients don’t fail therapy. But sometimes, therapy fails them. Read More
Published on June 19, 2015
Investigators at Children’s Hospital Los Angeles are providing new hope for babies with short bowel syndrome (SBS) by developing a novel model of SBS in zebrafish, described in a paper published online on June 18 by the American Journal of Physiology-Gastrointestinal and Liver... Read More
Published on June 18, 2015
Researchers at Children’s Hospital Los Angeles have demonstrated that adolescents and young adults with congenital adrenal hyperplasia (CAH) have significantly increased amounts of abdominal fat tissue, placing them at greater risk for harmful conditions linked to obesity,... Read More
Published on June 17, 2015
To help understand this paper, I had to draw a picture! Feel free to use as a reference.In a finding that furthers our understanding of human immunodeficiency virus (HIV), researchers from Children’s Hospital Los Angeles discovered two locations where a single difference in HIV’... Read More
Published on June 2, 2015
Facing the bleakest odds, Andreas Reiff, MD, helped launch a new age in the treatment of autoimmune disease.  During his fellowship, Reiff and others at CHLA helped discover the inflammatory signaling pathways of a substance called tumor necrosis factor (TNF); excess levels of... Read More
Published on May 24, 2015
At the 3rd Light Up the Blues Concert, emcee Jack Black introduced Pat Levitt, PhD, Simms/Mann Chair in Developmental Neurogenetics at Children’s Hospital Los Angeles. Dr. Levitt asked the audience, “How many of you have had, at least once in your life, really challenging... Read More
Published on May 19, 2015
A recent study—published online in the journal of Cancer Research on April 23—demonstrates that a growth factor called G-CSF, commonly used in high-risk neuroblastoma treatment, leads to increased tumor growth and metastasis by stimulating cancer stem cells in an experimental... Read More