COVID-19 Research

Published on April 25, 2022
Tiredness and fatigue. Frequent headaches. Brain fog. These are just a few symptoms of long COVID that can persist weeks after a COVID-19 infection. Find out how researchers at Children’s Hospital Los Angeles are studying new ways to manage and potentially treat long COVID. Read More
Published on February 17, 2022
How financially disadvantaged families are helping their kids build resilience. Read More
Published on October 22, 2020
One of the largest U.S. genetic studies of the virus, conducted at Children’s Hospital Los Angeles, supports public health decisions limiting contact Read More
Published on September 17, 2020
One of the mysteries about SARS-CoV-2, the virus that causes COVID-19, is how it is spread within households, including why some family members develop the viral infection and others do not. Is there a way to predict who will be symptomatic or asymptomatic and how long... Read More
Published on July 21, 2020
في مواجهة جائحة COVID-19 ، يجب إجراء تغييرات لكيفية إنعاش المرضى. الإجراءات المعتادة مثل التنبيب والإنعاش القلبي الرئوي يمكن أن تسمح بانتشار الفيروسات. قدمت جمعية القلب الأمريكية The American Heart Association تغييرات على الخطوات الإرشادية المسبقة لتقليل أو القضاء على كمية... Read More
Published on July 21, 2020
PhD  و Xiaowu Gai, PhD، قسم علم الأمراض والطب المخبري كان المرضى من مختلف الأعمار والأعراق ، و المواقع الجغرافية المختلفة ، يظهرون أنواعًا مختلفة من المرض وشدة الأعراض بسبب COVID-19. في حين كان يُعتقد في البداية أن الأطفال أقل تأثراً بالمرض من البالغين ، إلا أنه... Read More
Published on July 20, 2020
From basic research to epidemiological data, investigators in The Saban Research Institute of Children’s Hospital Los Angeles are taking on COVID-19 research from multiple directions.  Read More
Published on June 3, 2020
In the face of the COVID-19 pandemic, changes must be made to how patients are resuscitated. Normal procedures such as intubation and CPR can allow viruses to spread.  The American Heart Association has provided changes to prior guidelines to reduce or eliminate the amount of... Read More
Published on June 2, 2020
Patients of different ages and ethnicities, from a range of geographic locations, have been exhibiting varying types of illness and symptom severity due to COVID-19. While children were initially thought to be less affected by the disease than adults, they can recover from... Read More
Published on June 1, 2020
COVID-19 has required changes in every level of patient care as the nation strives to maintain safe intrapersonal distance. One way Children’s Hospital Los Angeles has addressed this issue is through the development and use of chatbots—software applications that mimic spoken... Read More
Published on May 31, 2020
In the most severe cases of COVID-19, patients suffer from acute respiratory distress syndrome (ARDS), which can be fatal. Ventilator management in ARDS is complicated, and randomized trials have demonstrated that failure to provide good lung-protective ventilation results in... Read More
Published on May 30, 2020
Early reports suggested that hydroxychloroquine (HCQ), a drug used to prevent malaria and treat children with certain rheumatologic conditions like lupus, may relieve inflammation associated with moderate or severe COVID-19. Michael Neely, MD, MSc, was lead investigator on a... Read More
Published on May 29, 2020
To fight a disease that is affecting the entire world, the disease must be better understood. Scientists and clinicians need data about the disease spectrum, optimal sample types for testing, and duration of virus shedding. Unfortunately, this type of information is quite... Read More
Published on May 28, 2020
COVID-19 is caused by the novel coronavirus, SARS-CoV-2, infecting the respiratory system. Specifically, the spike protein (S1 subunit) of the virus binds to a protein receptor called angiotensin converting enzyme 2 (ACE2) on lung epithelial cells. This interaction is a key step... Read More
Published on May 27, 2020
Since the onset of the COVID-19 pandemic, scientists and clinicians have sought to better understand the virus and how it spreads. Analysis of antibodies developed against the coronavirus can offer insight into timing and extent of illness. Read More
Published on May 26, 2020
The COVID-19 pandemic is a major stressor in the lives of the global community, but perhaps greatest for adolescents and young adults, who don’t always have resources to help them cope. To assess psychosocial stress and coping in adolescents, Ji-Ting Janet Yau, DO, has developed... Read More