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Hem-Onc Fellows Research Years

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Goals, Objectives and Tracks

Overall Description

During the second and third year, the fellow has ~80% protected time for research. Each fellow is assigned a specific Scholarly Oversight Committee (SOC) which, in conjunction with the research mentor and program director (PD), will provide guidance for their progress through a research project. The timeline for progress will vary depending on types of projects and areas of research chosen. But the fellow will prepare a written individualized research plan and present this to their SOC twice per year, outlining their progress and plans. It is the responsibility of the SOC and PD to assist each fellow in the progression.

Research Progression 

Step 1: Project development

Step 2: Project approval

Step 3: Data generation

Step 4: Data analysis and presentation

Step 5: Manuscript and grant submission

Clinical and Laboratory Projects

Each fellow will be expected to do the following:

Clinical Projects

1. Fellows will participate in the Core Curriculum on Scholarship Skills for fellows.
2. Fellows will attend the Ethics and Scientific Accountability Course at the Saban Research Institute.
3. Fellows will attend courses at the University of Southern California towards a Masters in Clinical Investigation or Masters in Public Health, as appropriate.
4. Fellows will write a formal research proposal for submission to the Committee on Clinical Investigation  (CCI).
5. Fellows will submit data as it matures for presentation at regional and national meetings.
6. Fellows will submit grants for project funding to institutional, regional and national funding organizations, as appropriate.
7. Fellows will submit for peer-reviewed publication project data, as it matures.

    Laboratory Projects

1. Fellows will participate in the Core Curriculum on Scholarship Skills for fellows.
2. Fellows will attend the Ethics and Scientific Accountability Course at the Saban Research Institute.
3. Fellows will write a formal research proposal for submission to the Committee
on Clinical Investigation, if appropriate.
4. Fellows will submit data as it matures for presentation at regional and national
meetings.
5. Fellows will submit grants for project funding to institutional, regional and
national funding organizations, as appropriate.
6. Fellows will submit for peer-reviewed publication project data, as it matures.

Fourth Year

Fellows may have the option of staying for a fourth year in fellowship to complete their research project but are expected to submit salary-supporting grants during their third year that would provide funds beginning some time during year four.

Recent Fellow Publications

1. Armenian SH, Nash KA, Kapoor N, Franklin JL, Gaynon PS, Ross LA, Hoffman JA. Prospective monitoring for invasive aspergillosis using galactomannan and polymerase chain reaction in high risk pediatric patients. Journal of Pediatric Hematology Oncology, 31:920-926, 2009. PMID: 19855303.

2. Gruber TA, Shah AJ, Hernandez M, Crooks GM, Abdel-Azim H, Gupta S, McKnight S, White D, Kapoor N, Kohn DB. Clinical and genetic heterogeneity in Omenn syndrome and severe combined immune deficiency. Pediatric Transplantation, 13:244-250, 2009. PMID: 18822103.

3. KoRH, JiL, BarnetteP, BostromB, HutchinsonR, RaetzE, SeibelNL, TwistCJ, EckrothE, SpostoR, GaynonPS, Loh ML. Outcome of patients treated for relapsed or refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium study. J Clin Oncol. 2010 Feb 1;28(4):648-54. Epub 2009 Oct 19. PMID:19841326.

4. RobisonNJ, DawlabaniN, LastraCR, DhallG. Cerebral sinus thrombosis in a child with active ulcerative colitis and factor V Leiden. Pediatr Blood Cancer. 2009 Jul;52(7):867-9. 19260108.

5. John A van Doorninck, Lingyun Ji, Betty Schaub, Hiroyuki Shimada, Michele R Wing, Mark D Krailo, Stephen L Lessnick, Neyssa Marina, Timothy J Triche, Richard Sposto, Richard B Womer, Elizabeth R Lawlor.  Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children’s Oncology Group.  J Clin Oncol. 28(12):1289-94. 2010.

6. Etan Orgel, Shveta Jain, Lingyun Ji, Liora Pollick, Stephanie Si, Jonathan Finlay, David R Freyer.  Hearing loss among survivors of childhood brain tumors treated with an irradiation-sparing approach.  Pediatr Blood Cancer. 2011.  Accepted for publication.

7. S K Baniwal, P K Shah, Y Shi, J H Haduong, Y A Declerck, Y Gabet, B Frenkel.  Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells.  Osteoporosis International. 2011.  Accepted for publication.

Grants Obtained by Current and Recent Fellows

  • Batul Suterwala   
    St. Baldricks funding for two years
  • Josie Haduong  
    Institutional T32 NIH Training Grant funding for two years
  • Etan Orgel 
    Translational Research Program Award from the Leukemia & Lymphoma Society Co-investigator
  • Chintan Parekh 
    St. Baldricks funding for two years
  • Hung Tran    
    Hyundai Cure on Wheels funding for one year