Publications

Research Based on Work Completed in the Developmental Biology and Regenerative Medicine Laboratories of The Saban Research Institute

Arany, PR, Tuan, TL. Wound Care and Sciences (Wound Healing Society Year Book). Vol. 2. Sen CK, editor: Mary Ann Liebert; 2010. Targeted approaches to scar management based on our current understanding of triggers, modulators, and effectors of aberrant healing.

Arciero J, Ermentrout GB, Upperman JS, Vodovotz Y, Rubin JE. Using a mathematical model to analyze the role of probiotics and inflammation in necrotizing enterocolitis. PloS One. 2010 Apr 19;5(4);e10066. PMID: 20419099.

Berg T, Delanghe S, Al Alam D, Utley S, Estrada J, Wang KS. B-Catenin regulates mesenchymal progenitor cell differentiation during hepatogenesis. J Surg Res. 2010 Dec;164(2):276-85. Epub 2009 Nov 14.

Carraro G, del Moral PM, Warburton D. Mouse embryonic lung culture, a system to evaluate the molecular mechanisms of branching. J Vis Exp. 2010 Jun 30;(40). pii: 2035. doi: 10.3791/2035. PMID: 20644505.

Carraro G, El-Hashash A, Guidolin D, Tiozzo C, Turcatel G, Young BM, De Langhe SP, Bellusci S, Shi W, Parnigotto PP, Warburton D. miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol. 2009 Sep 15;333(2):238-50. Epub 2009 Jun 25. PMID: 19559694; PMCID: PMC2735610.

Chokshi NK, Simeone DM, Chari RS, Dorey F, Guner YS, Upperman JS. A survey of academic surgeons: work, stress, and research. Surgery. 2009 Sep;146(3):462-8.

Chung S, Kang DO, Yamzon J, Warburton D, Koh CJ. O-GlcNAc mediated glycosylation down-regulation in mice with cyclophosphamide induced cystitis. J Urol. 2010 Jan;183(1):351-6. PMID: 19914650; PMCID: PMC2840040.

Cobb JP, Cairns CB, Bulger E, Wong HR, Parsons PE, Angus DC, Gentile NT, Hoyt DB, Schwinn DA, Wiener-Kronish JP, Upperman JS. The United States critical illness and injury trials group: an introduction. J. Trauma-Injury Infection & Critical Care. 2009 Aug;67(2 Suppl):S159-60.

Cryer HG, Hiatt JR, Eckstein M, Chidester C, Raby S, Ernst TG, Marguiles D, Putnam B, Demtriades D, Gaspard D, Singh R, Saad S, Samuel C, Upperman JS. Improved trauma system multicasualty incident response: comparison of two train crash disasters. J Trauma 2010 April;68(4):783-9. PMID: 20386274.

Cunnick JM, Schmidhuber S, Chen G, Yu M, Yi SJ, Cho YJ, Kaartinen V, Minoo P, Warburton D, Groffen J, Heisterkamp N. Bcr and Abr cooperate in negatively regulating acute inflammatory responses. Mol Cell Biol. 2009 Nov;29(21):5742-50. Epub 2009 Aug 24. PMID: 19703997; PMCID: PMC2772743.

Del Moral PM, Warburton D. Explant culture of mouse embryonic whole lung, isolated epithelium, or mesenchyme under chemically defined conditions as a system to evaluate the molecular mechanism of branching morphogenesis and cellular differentiation. Methods Mol Biol. 2010;633:71-9. PMID: 20204620.

Da Sacco S, Sedrakyan S, Boldrin F, Giuliani S, Parnigotto P, Habibian R, Warburton D, De Filippo RE, Perin L. Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications. J Urol. 2010 Mar;183(3):1193-200. Epub 2010 Jan 22. PMID: 20096867.

El-Hashash AH, Warburton D, Kimber SJ. Genes and signals regulating murine trophoblast cell development. Mech Dev. 2010 Jan-Feb;127(1-2):1-20. Epub 2009 Sep 13. PMID: 19755154; PMCID: PMC2865247.

Emami CN, Petrosyan M, Giuliani S, Williams M, Hunter C, Prasadarao NV, Ford, HR. Role of the host defense system and intestinal microbial flora in the pathogenesis of necrotizing enterocolitis. Surg Infect (Larchmt) 2009 Oct;10(5):407-417. PMID: 19943775; PMCID: PMC2956528.

Ferrer R, Balasuriya D, Iverson E, Upperman JS. Pediatric disaster preparedness of a hospital network in a large metropolitan region. Am J Disaster Med. 2010 Jan-Feb;5(1):27-34. PMID: 20349700.

Giuliani S, Pierce J, Franklin A, Ford H, Grikscheit TC. Massive subcutaneous emphysema, pneumomediastinum, and pneumopericardium in children. J Pediatr Surg. 2010 Mar;45(3):647-9. PMID: 20223337.

Gold JI, Montano Z, Shields S, Mahrer NE, Vibhakar V, Ybarra T, Yee N, Upperman JS, Blake N, Stevenson K, Nager AL. Pediatric disaster preparedness in the medical setting: integrating mental health. Am J Disaster Med. 2009 May-Jun;4(3):137-46. PMID: 19739456.

Goodhue CJ, Burke RV, Chambers S, Ferrer RR, Upperman JS. Disaster olympix: a unique nursing emergency preparedness exercise. J Trauma Nurs. 2010 Jan-Mar;17(1):5-10. PMID: 20234232.

Guner YS, Khemani RG, Qureshi FG, Wee CP, Austin MT, Dorey F, Rycus PT, Ford HR, Friedlich P, Stein JE. Outcome analysis of neonates with congenital diaphragmatic hernia treated with venovenous vs venoarterial extracorporeal membrane oxygenation. J Pediatr Surg. 2009 Sept;44(9):1691-701. PMID: 19735810.

Guner YS, Friedlich P, Wee CP, Dorey F, Camerini V, Upperman JS. State-based analysis of necrotizing enterocolitis outcomes. J Surg Res. 2009 Nov;157(1):21-9. Epub 2008 Dec 4. PMID: 19615694.

Gupte VV, Ramasamy SK, Reddy R, Lee J, Weinreb PH, Violette SM, Guenther A, Warburton D, Driscoll B, Minoo P, Bellusci S. Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Respir Crit Care Med. 2009 Sep 1;180(5):424-36. Epub 2009 Jun 4. PMID: 19498056; PMCID: PMC2742760.

Hunter CJ, Petrosyan M, Connelly ME, Ford HR, Nguyen NX. Repair of long-gap esophageal atresia: gastric conduits may improve outcome-a 20-year single center experience. Pediatr Surg Int. 2009 Aug 26. [Epub ahead of print]. PMID: 19707773; PMCID: PMC2777230.

Iwata JI, Hosokawa R, Sanchez-Lara PA, Urata M, Slavkin H, Chai Y. Transforming growth factor beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells. J Biol Chem. 2010 Feb 12;285(7):4975-82. Epub 2009 Dec 3. PMID: 19959467.

Jackson S, Warburton D, Driscoll B. Telomerase null mice exhibit attenuation of alveolar type 2 cell expansion following partial pneumonectomy. J Surg Res. 2010 Feb;158(2):199. doi: 10.1016/j.jss.2009.11.089.

Jiang TX, Tuan TL, Wu P, Chuong, CM. Formation of skin appendage: involvement of matrix metalloproteinases in feather follicle development. (Developmental Dynamics 2010; under revision).

Kim J, Wu Q, Zhang Y, Wiens KM, Huang Y, Rubin N, Shimada H, Handin RI, Chao MY, Tuan TL, Starnes VA and Lien CL. PDGF signaling is required for epicardial function and new blood vessel formation in regenerating zebrafish hearts. Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17206-10. Epub 2010 Sep 21. PMID: 20858732; PMCID: PMC2951463.

Lee J, Reddy R, Barsky L, Scholes J, Chen H, Shi W, Driscoll B. Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice. Am J Physiol Lung Cell Mol Physiol. 2009 Jan;296:L57-70. Epub 2008 Oct. 24. PMID: 18952756; PMCID: PMC2636955.

Lemley KV. Kidney disease in nail-patella syndrome. Pediatr Nephrol. 2009 Dec;24(12):2345-54. Epub 2008 Jun 6. PMID: 18535845; PMCID: PMC2770138.

Lemley KV. Pediatrics: how 'minimal' are the adult consequences of childhood MCNS? Nat Rev Nephrol. 2010 Feb;6(2):70-1. PMID: 20111047.

Lu L, Wang J, Zhang F, Chai Y, Brand D, Wang X, Horwitz DA, Shi W, Zheng SG. Role of Smad and non-Smad signals in the development of Th17 and regulatory T cells. J Immunol. 2010 Apr 15;184(8):4295-306. Epub 2010 Mar 19. PMID: 20304828.

Maciewicz RA, Warburton D, Rennard SI. Can increased understanding of the role of lung development and aging drive new advances in chronic obstructive pulmonary disease? Proc Am Thorac Soc. 2009 Dec 1;6(7):614-7. PMID: 19934358.

Mackoff R, Iverson E, Kiekel P, Dorey F, Upperman JS, Metzenberg A. Attitudes of genetic counselors towards genetic susceptibility testing in children. J Genet Couns. 2010 Aug;19(4):402-16. PMID: 20390328.

Mahavadi P, Korfei M, Henneke I, Liebisch G, Schmitz G, Gochuico BR, Markart P, Bellusci S, Seeger W, Ruppert C, Guenther A. Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia. Am J Respir Crit Care Med. 2010 Jul 15;182:207-19.

Matthews JA, Grikscheit TC. Key intestinal stem cell niche components are identified in human intestine during necrotizing enterocolitis. J Surg Res. 2010;158(2):277-9.

Neches R, Ryutov T, Kichkaylo T, Burke RV, Claudius IA, Upperman JS. Design and evaluation of a disaster preparedness logistics tool. Am J Disaster Med. 2009 Nov-Dec;4(6):309-20.

Perin L, Sedrakyan S, Giuliani S, Da Sacco S, Carraro G, Shiri L, Lemley KV, Rosol M, Wu S, Atala A, Warburton D, De Filippo RE. Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis. PLoS One. 2010 Feb 24;5(2):e9357. PMID: 20195358; PMCID: PMC2827539.

Petrosyan M, Estrada J, Hunter C, Woo R, Stein J, Ford HR, Anselmo DM. Esophageal atresia/tracheoesophageal fistula in very low-birth-weight neonates: improved outcomes with staged repair. J Pediatr Surg. 2009 Dec;44(12):2278-81. PMID: 20006009.

Petrosyan M, Guner YS, Emami CN, Ford HR. Disparities in the delivery of pediatric trauma care. J Trauma 2009 Aug;67(2 Suppl):S114-9. PMID: 19667843.

Petrosyan M, Hunter C, Estrada J, Guner Y, Qureshi F, Stein J, Ford HR, Wang K, Nguyen N. Subcutaneous fixation of gastrostomy tube is superior to temporary fixation. J Laparoendosc Adv Surg Tech A. 2010 Mar;20(2):207-9. PMID: 19811061.

Pieretti-Vanmarcke R, Velmahos GC, Nance ML, Islam S, Falcone RA Jr, Wales PW, Brown RL, Gaines BA, McKenna C, Moore FO, Goslar PW, Inaba K, Barmparas G, Scaife ER, Metzger RR, Brockmeyer DL, Upperman JS, Estrada J, Lanning DA, Rasmussen SK, Danielson PD, Hirsh MP, Consani HF, Stylianos S, Pineda C, Norwood SH, Bruch SW, Drongowski R, Barraco RD, Pasquale MD, Hussain F, Hirsch EF, McNeely PD, Fallat ME, Foley DS, Iocono JA, Bennett HM, Waxman K, Kam K, Bakhos L, Petrovick L, Chang Y, Masiakos PT. Clinical clearance of the cervical spine in blunt trauma patients younger than 3 years: a multi-center study of the american association for the surgery of trauma. J Trauma. 2009 Sep;67(3):543-9; discussion 549-50.

Rennard SI, Warburton D. Introduction: Ninth Lund COPD Symposium. Proc Am Thorac Soc. 2009 Dec 1;6(7):557. PMID: 19934348.

Rice DP, Connor EC, Veltmaat JM, Lana-Elola E, Veistinen L, Tanimoto Y, Bellusci S, Rice R. Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet. 2010 Sep 1;19(17):3457-67. Epub 2010 Jun 22. PMID: 20570969. PMCID: PMC2916710.

Rodriguez KA, Goodhue CJ, Upperman JS. Pediatric nurse practitioner implementation of a pediatiric trauma continuity clinic utilizing the “medical home” model. J Trauma Nurs. 2010 Apr-Jun;17(2):64-6; quiz 67-8. PMID: 20559050.

Sala FG, Matthews JA, Speer AL, Grikscheit TC. Murine tissue-engineered small intestine demonstrates intact tight and adherens junctions. J Surg Res. 2010;158(2):199.

Sanchez-Lara PA, Carmichael SL, Graham JM Jr, Lammer EJ, Shaw GM, Ma C, Rasmussen SA; National Birth Defects Prevention Study. Fetal constraint as a potential risk factor for craniosynostosis. Am J Med Genet A. 2010 Feb;152A(2):394-400. PMID: 20101684; PMCID: PMC2815148.

Sharma S, Tantisira K, Carey V, Murphy AJ, Lasky-Su J, Celedón JC, Lazarus R, Klanderman B, Rogers A, Soto-Quirós M, Avila L, Mariani T, Gaedigk R, Leeder S, Torday J, Warburton D, Raby B, Weiss ST. A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma. Am J Respir Crit Care Med. 2010 Feb 15;181(4):328-36. Epub 2009 Nov 19. PMID: 19926868; PMCID: PMC2822972.

Shi W, Xu J, Warburton D. Development, repair and fibrosis: what is common and why it matters. Respirology. 2009 Jul;14(5):656-65. PMID: 19659647; PMCID: PMC2747658.

Speer AL, Sala FG, Matthews JA, Grikscheit TC. Intestinal subepithelial myofibroblasts demonstrate Cox-2 expression in early stages of epithelial proliferation in tissue engineered small intestine. J Surg Res. 2010;158(2):199-200.

Tai CC, Curtis JL, Sala FG, Del Moral PM, Choksi N, Kanard RJ, Al Alam D, Wang J, Burns RC, Ford HR, Grishin A, Wang KS, Bellusci S. Induction of fibroblast growth factor 10 (FGF10) in the ileal crypt epithelium after massive small bowel resection suggests a role for FGF10 in gut adaptation. Dev Dyn. 2009 Feb;238 (2):294-301. PMID: 18773490.

Tai CC, Sala FG, Ford HR, Wang KS, Li C, Minoo P, Grikscheit TC, Bellusci S. Wnt5a knock-out mouse as a new model of anorectal malformation. J Surg Res. 2009; Oct;156(2):278-82. Epub 2009 May 8. PMID: 19577771.

Tiozzo C, De Langhe S, Carraro G, Alam DA, Nagy A, Wigfall C, Hajihosseini MK, Warburton D, Minoo P, Bellusci S. Fibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome. Pediatr Res. 2009 Oct;66(4):386-90. PMID: 19581825.

Tiozzo C, De Langhe S, Yu M, Londhe VA, Carraro G, Li M, Li C, Xing Y, Anderson S, Borok Z, Bellusci S, Minoo P. Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury Am J Respir Crit Care Med. 2009 Oct 15;180(8):701-12. Epub 2009 Jul 2. PMID: 19574443; PMCID: PMC2778148.

Upperman JS, Berg B. Introduction pediatric disaster and emergency services national summit. J Trauma. 2009 Aug;67(2 Suppl):S71-2. PMID: 19667855.

Wang J, Ford HR, Grishin AV. NF-kappaB-mediated expression of MAPK phosphatase-1 is an early step in desensitization to TLR ligands in enterocytes. Mucosal Immunol. 2010 Sep;3(5):523-34. Epub 2010 Jun 16. PMID: 20555314.

Wang J, Ouyang Y, Guner Y, Ford HR, Grishin AV. Ubiquitin-editing enzyme A20 promotes tolerance to lipopolysaccharide in enterocytes. J Immunol. 2009 Jul 15;183(2):1384-92. Epub 2009 Jul 1. PMID: 19570823; PMCID: PMC2739219.

Warburton D, El-Hashash A, Carraro G, Tiozzo C, Sala F, Rogers O, De Langhe S, Kemp PJ, Riccardi D, Torday J, Bellusci S, Shi W, Lubkin SR, Jesudason E. Lung organogenesis. Curr Top Dev Biol. 2010;90:73-158. PMID: 20691848.

Xing Y, Li C, Sridurongrit S, Tiozzo C, Bellusci S, Borok Z, Kaartinen V, Minoo P. 2010 Signaling via Alk5 controls the ontogeny of lung Clara cells. Development. 2010 Mar;137(5):825-833. PMID: 20147383. PMCID: PMC2827691.