Cancer Scholarly Publications

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Allen J, Donahue B, Mehta M, Miller DC, Rorke LB, Jakacki R, Robertson P, Sposto R, Holmes E, Vezina G, Muraszko K, Puccetti D, Prados M, Chan KW. A phase II study of preradiotherapy chemotherapy followed by hyperfractionated radiotherapy for newly diagnosed high-risk medulloblastoma/primitive neuroectodermal tumor: a report from the Children's Oncology Group (CCG 9931). Int J Radiat Oncol Biol Phys. 2009 Jul 15;74(4):1006-11. Epub 2009 Apr 7. PMID: 19356859; PMCID: PMC2739055.

Anderson JR, Barr FG, Hawkins DS, Parham DM, Skapek SX, Triche TJ. Fusion-negative alveolar rhabdomyosarcoma: modification of risk stratification is premature. J Clin Oncol. 2010 Oct 10;28(29):e587-8; author reply e589-90. Epub 2010 Aug 9.  PMID: 20697086.

Ara T, DeClerck YA. Interleukin-6 in bone metastasis and cancer progression. Eur J Cancer. 2010 May;46(7):1223-31. Epub 2010 Mar 23. PMID: 20335016; PMCID: PMC2917917.

Ara T, Song L, Shimada H, Keshelava N, Russell HV, Metelitsa LS, Groshen SG, Seeger RC, DeClerck YA. Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res. 2009 Jan 1;69(1):329-37. PMID: 19118018; PMCID: PMC2761219.

Armenian SH, Nash KA, Kapoor N, Franklin JL, Gaynon PS, Ross LA, Hoffman JA. Prospective monitoring for invasive aspergillosis using galactomannan and polymerase chain reaction in high risk pediatric patients. J Pediatr Hematol Oncol. 2009 Dec;31(12):920-6. PMID: 19855303.

Askins MA, Sahler OJ, Sherman SA, Fairclough DL, Butler RW, Katz ER, Dolgin MJ, Varni JW, Noll RB, Phipps S. Report from a multi-institutional randomized clinical trial examining computer-assisted problem-solving skills training for English- and Spanish-speaking mothers of children with newly diagnosed cancer. J Pediatr Psychol. 2009 Jun;34(5):551-63. Epub 2008 Dec 17. PMID: 19091804; PMCID: PMC2684487.

Avramis VI, Avramis EV, Hunter W, Long MC. Immunogenicity of native or pegylated E. coli and Erwinia asparaginases assessed by ELISA and surface plasmon resonance (SPR-biacore) assays of IgG antibodies (Ab) in sera from patients with acute lymphoblastic leukemia (ALL). Anticancer Res. 2009 Jan;29(1):299-302. PMID: 19331165.

Baker DL, Schmidt ML, Cohn SL, Maris JM, London WB, Buxton A, Stram D, Castleberry RP, Shimada H, Sandler A, Shamberger RC, Look AT, Reynolds CP, Seeger RC, Matthay KK; Children's Oncology Group. Outcome after reduced chemotherapy for intermediate-risk neuroblastoma. N Engl J Med. 2010 Sep 30;363(14):1313-23. PMID: 20879880.

Behan JW, Avramis VI, Yun JP, Louie SG, Mittelman SD. Diet-induced obesity alters vincristine pharmacokinetics in blood and tissues of mice. Pharmacol Res. 2010 May;61(5):385-90. Epub 2010 Jan 18. PMID: 20083201 PMCID; PMC2848885.

Behan JW, Yun JP, Proektor MP, Ehsanipour EA, Arutyunyan A, Moses AS, Avramis VI, Louie SG, Butturini A, Heisterkamp N, Mittelman SD. Adipocytes impair leukemia treatment in mice. Cancer Res. 2009 Oct 1;69(19):7867-74. Epub 2009 Sep 22. PMID: 19773440; PMCID: PMC2756308.

Beiske K, Burchill SA, Cheung IY, Hiyama E, Seeger RC, Cohn SL, Pearson AD, Matthay KK, International Neuroblastoma Risk Group Task Force. Consensus criteria for sensitive detection of minimal neuroblastoma cells in bone marrow, blood and stem cell preparations by immunocytology and QRT-PCR: recommendations by the International Neuroblastoma Risk Group Task Force. Br J Cancer. 2009 May 19;100(10):1627-37. Epub 2009 Apr 28. PMID: 19401690; PMCID: PMC2696761.

Bennani-Baiti IM, Cooper A, Lawlor ER, Kauer M, Ban J, Aryee DN, Kovar H. Intercohort gene expression co-analysis reveals chemokine receptors as prognostic indicators in Ewing's sarcoma. Clin Cancer Res. 2010 Jul 15;16(14):3769-78. Epub 2010 Jun 4. PMID: 20525755; PMCID: PMC2905506.

Bensimhon P, Villablanca JG, Sender LS, Matthay KK, Park JR, Seeger R, London WB, Yap JS, Kreissman SG. Peripheral blood stem cell support for multiple cycles of dose intensive induction therapy is feasible with little risk of tumor contamination in advanced stage neuroblastoma: a report from the Childrens Oncology Group. Pediatr Blood Cancer. 2010 Apr;54(4):596-602. PMID: 20049927; PMCID: PMC2905158.

Bergfeld SA, DeClerck YA. Bone marrow-derived mesenchymal stem cells and the tumor microenvironment. Cancer Metastasis Rev. 2010 Jun;29(2):249-61. PMID: 20411303.

Blavier L, Lazaryev A, Shi XH, Dorey FJ, Shackleford GM, DeClerck YA. Stromelysin-1 (MMP-3) is a target and a regulator of Wnt1-induced epithelial-mesenchymal transition (EMT). Cancer Biol Ther. 2010 Jul 15;10(2):198-208. Epub 2010 Jul 29. PMID: 20534975.

Butturini AM, Frappaz D. The challenges of high-dose chemotherapy in CNS tumors. Pediatr Blood Cancer. 2010 Apr;54(4):652-3. PMID: 20146215.

Butturini AM, Jacob M, Aguajo J, Vander-Walde NA, Villablanca J, Jubran R, Erdreich-Epstein A, Marachelian A, Dhall G, Finlay JL. High-dose chemotherapy and autologous hematopoietic progenitor cell rescue in children with recurrent medulloblastoma and supratentorial primitive neuroectodermal tumors: the impact of prior radiotherapy on outcome. Cancer. 2009 Jul 1;115(13):2956-63. PMID: 19402050.

Capasso M, Devoto M, Hou C, Asgharzadeh S, Glessner JT, Attiyeh EF, Mosse YP, Kim C, Diskin SJ, Cole KA, Bosse K, Diamond M, Laudenslager M, Winter C, Bradfield JP, Scott RH, Jagannathan J, Garris M, McConville C, London WB, Seeger RC, Grant SF, Li H, Rahman N, Rappaport E, Hakonarson H, Maris JM. Common variations in BARD1 influence susceptibility to high-risk neuroblastoma. Nat Genet. 2009 Jun;41(6):718-23. Epub 2009 May 3. PMID: 19412175; PMCID: PMC2753610.

Chen HJ, Panigrahy A, Dhall G, Finlay JL, Nelson MD Jr, Bluml S. Apparent diffusion and fractional anisotropy of diffuse intrinsic brain stem gliomas. AJNR Am J Neuroradiol. 2010 Nov;31(10):1879-85. Epub 2010 Jul 1. PMID: 20595371.

Chen TT, Rakheja D, Hung JY, Hornsby PJ, Tabaczewski P, Malogolowkin M, Feusner J, Miskevich F, Schultz R, Tomlinson GE. Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor. Pediatr Blood Cancer. 2009 Dec;53(6):1040-7.

Chi F, Wang Y, Gallaher TK, Wu CH, Jong A, Huang SH. Identification of IbeR as a stationary-phase regulator in meningitic Escherichia coli K1 that carries a loss-of-function mutation in rpoS. J Biomed Biotechnol. 2009;2009:520283. PMID: 19637320.

Cunnick JM, Schmidhuber S, Chen G, Yu M, Yi SJ, Cho YJ, Kaartinen V, Minoo P, Warburton D, Groffen J, Heisterkamp N. Bcr and Abr cooperate in negatively regulating acute inflammatory responses. Mol Cell Biol. 2009 Nov;29(21):5742-50. Epub 2009 Aug 24. PMID: 19703997; PMCID: PMC2772743.

Davicioni E, Anderson MJ, Finckenstein FG, Lynch JC, Qualman SJ, Shimada H, Schofield DE, Buckley JD, Meyer WH, Sorensen PH, Triche TJ. Molecular classification of rhabdomyosarcoma--genotypic and phenotypic determinants of diagnosis: a report from the Children's Oncology Group. Am J Pathol. 2009 Feb;174(2):550-64. PMID: 19147825; PMCID: PMC2630563.

Davicioni E, Anderson JR, Buckley JD, Meyer WH, Triche TJ. Gene expression profiling for survival prediction in pediatric rhabdomyosarcomas: a report from the Children's Oncology Group. J Clin Oncol. 2010 Mar 1;28(7):1240-6. Epub 2010 Feb 1. PMID: 20124188.

Davidson L, Gonzalez-Gomez I, McComb JG. Completely intraosseous atretic meningocele. Pediatr Neurosurg. 2009;45(4):308-10. Epub 2009 Aug 19. PMID: 19690448.

Davidson L, Gonzalez-Gomez I, McComb JG. Thoracic spinal cord tethering resulting from an exophytic hamartoma. Pediatr Neurosurg. 2009;45(3):244-6. Epub 2009 Jun 15. PMID: 19521140

Delgado DC, Hank JA, Kolesar J, Lorentzen DF, Gan J, Seo S, Kim K, Shusterman S, Gillies SD, Reisfeld RA, Yang RK, Gadbaw B, Desantes KB, London WB, Seeger RC, Maris JM, Sondel PM. Genotypes of NK cell KIR receptors, their ligands, and Fc{gamma} receptors in the response of neuroblastoma patients to Hu14.18-IL2 immunotherapy. Cancer Res. 2010 Dec 1;70(23):9554-61. Epub 2010 Oct 8. PMID: 20935224; PMCID: PMC2999644.

Dhall G. Medulloblastoma. J Child Neurol. 2009 Nov;24(11):1418-30. PMID: 19841429.

Dunkel IJ, Gardner SL, Garvin JH Jr, Goldman S, Shi W, Finlay JL. High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma. Neuro Oncol. 2010 Mar;12(3):297-303. Epub 2010 Jan 11. PMID: 20167818; PMCID: PMC2940591.

Dunkel IJ, Jubran RF, Gururangan S, Chantada GL, Finlay JL, Goldman S, Khakoo Y, O'Brien JM, Orjuela M, Rodriguez-Galindo C, Souweidane MM, Abramson DH. Trilateral retinoblastoma: potentially curable with intensive chemotherapy. Pediatr Blood Cancer. 2010 Mar;54(3):384-7. PMID: 19908299.

Evdokimova V, Tognon C, Ng T, Ruzanov P, Melnyk N, Fink D, Sorokin A, Ovchinnikov LP, Davicioni E, Triche TJ, Sorensen PH. Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition. Cancer Cell. 2009 May 5;15(5):402-15. PMID: 19411069.

Fei F, Stoddart S, Groffen J, Heisterkamp N. Activity of the Aurora kinase inhibitor VX-680 against Bcr/Abl-positive acute lymphoblastic leukemias. Mol Cancer Ther. 2010 May;9(5):1318-27. Epub 2010 Apr 13. PMID: 20388735; PMCID: PMC2868097.

Fei F, Stoddart S, Muschen M, Kim YM, Groffen J, Heisterkamp N. Development of resistance to dasatinib in Bcr/Abl-positive acute lymphoblastic leukemia. Leukemia. 2010 Apr;24(4):813-20. Epub 2010 Jan 28. PMID: 20111071.

Ferrario A, Gomer CJ. Targeting the 90 kDa heat shock protein improves photodynamic therapy. Cancer Lett. 2010 Mar 28;289(2):188-94. PMID: 19733005; PMCID: PMC2829337. 

Ferrario A, Gomer CJ. Targeting the tumor microenvironment using photodynamic therapy combined with inhibitors of cyclooxygenase-2 or vascular endothelial growth factor. Methods Mol Biol. 2010;635:121-32. PMID: 20552344.

Finlay JL, Massimino M. A consensus and state-of-the-art workshop: marrow ablative chemotherapy with hematopoietic cell rescue for malignant brain tumors of childhood and adolescence. Pediatr Blood Cancer. 2010 Apr;54(4):634. PMID: 20146221.

Freyer DR. Transition of care for young adult survivors of childhood and adolescent cancer: rationale and approaches. J Clin Oncol. 2010 Nov 10 ;28(32):4810-8. Epub 2010 Mar 29. PMID: 20351333.

Freyer DR, Sung L, Reaman GH. Prevention of hearing loss in children receiving cisplatin chemotherapy. J Clin Oncol. 2009 Jan 10;27(2):317-8; author reply 318-9. Epub 2008 Dec 8. PMID: 19064953.

Gaynon PS, Angiolillo AL, Carroll WL, Nachman JB, Trigg ME, Sather HN, Hunger SP, Devidas M. Long-term results of the Children's Cancer Group studies for childhood acute lymphoblastic leukemia 1983-2002: a Children's Oncology Group Report. Leukemia. 2010 Feb;24(2):285-97. Epub 2009 Dec 17. PMID: 20016531.

Gilsanz V, Chalfant J, Mo AO, Lee DC, Dorey FJ, Mittelman SD. Reciprocal relations of subcutaneous and visceral fat to bone structure and strength. J Clin Endocrinol Metab. 2009 Sep;94(9):3387-93. Epub 2009 Jun 16. PMID: 19531595; PMCID: PMC2741723.

Gorman MF, Ji L, Ko RH, Barnette P, Bostrom B, Hutchinson R, Raetz E, Seibel NL, Twist CJ, Eckroth E, Sposto R, Gaynon PS, Loh ML. Outcome for children treated for relapsed or refractory acute myelogenous leukemia (rAML): a Therapeutic Advances in Childhood Leukemia (TACL) Consortium study. Pediatr Blood Cancer. 2010 Sep;55(3):421-9. PMID: 20658611.

Gunther OP, Balshaw RF, Scherer A, Hollander Z, Mui A, Triche TJ, Freue GC, Li G, Ng RT, Wilson-McManus J, McMaster WR, McManus BM, Keown PA, Biomarkers in Transplantation Team. Functional genomic analysis of peripheral blood during early acute renal allograft rejection. Transplantation. 2009 Oct 15;88(7):942-51. PMID: 19935467.

Holzel M, Huang S, Koster J, Ora I, Lakeman A, Caron H, Nijkamp W, Xie J, Callens T, Asgharzadeh S, Seeger RC, Messiaen L, Versteeg R, Bernards R. NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome. Cell. 2010 Jul 23;142(2):218-29. PMID: 20655465; PMCID: PMC2913027.

Horton TM, Sposto R, Brown P, Reynolds CP, Hunger SP, Winick NJ, Raetz EA, Carroll WL, Arceci RJ, Borowitz MJ, Gaynon PS, Gore L, Jeha S, Maurer BJ, Siegel SE, Biondi A, Kearns PR, Narendran A, Silverman LB, Smith MA, Zwaan CM, Whitlock JA; ALLNA 2008 Conference. Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference. Pediatr Blood Cancer. 2010 Jul 1;54(7):872-8. PMID: 20127846; PMCID: PMC2857540.

Hu H, Du L, Nagabayashi G, Seeger RC, Gatti RA. ATM is down-regulated by N-Myc-regulated microRNA-421. Proc Natl Acad Sci USA. 2010;107(4):1506-11.

Hu K, Lee C, Qiu D, Fotovati A, Davies A, Abu-Ali S, Wai D, Lawlor ER, Triche TJ, Pallen CJ, Dunn SE. Small interfering RNA library screen of human kinases and phosphatases identifies polo-like kinase 1 as a promising new target for the treatment of pediatric rhabdomyosarcomas. Mol Cancer Ther. 2009 Nov;8(11):3024-35. Epub 2009 Nov 3. PMID: 19887553; PMCID: PMC2783569.

Huang S, Laoukili J, Epping MT, Koster J, Holzel M, Westerman BA, Nijkamp W, Hata A, Asgharzadeh S, Seeger RC, Versteeg R, Beijersbergen RL, Bernards R. ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome. Cancer Cell. 2009 Apr 7;15(4):328-40. PMID: 19345331; PMCID: PMC2693316.

Huang SH, He L, Zhou Y, Wu CH, Jong A. Lactobacillus rhamnosus GG suppresses meningitic E. coli K1 penetration across human intestinal epithelial cells in vitro and protects neonatal rats against experimental hematogenous meningitis. Int J Microbiol. 2009;2009:647862. Epub 2008 Nov 24. PMID: 20016677; PMCID: PMC2775688.

Huang SH, Jong A. Evolving role of laminin receptors in microbial pathogenesis and therapeutics of CNS infection. Future Microbiol. 2009 Oct;4(8):959-62. PMID: 19824788.

Imran H, Enders F, Krailo M, Sim F, Okuno S, Hawkins D, Neglia J, Randall RL, Womer R, Mascarenhas L, Arndt CA. Effect of time to resumption of chemotherapy after definitive surgery on prognosis for non-metastatic osteosarcoma. J Bone Joint Surg Am. 2009 Mar 1;91(3):604-12. PMID: 19255220; PMCID: PMC2701597.

Iobst EA, Alderfer MA, Sahler OJ, Askins MA, Fairclough DL, Katz ER, Butler RW, Dolgin MJ, Noll RB. Problem solving and maternal distress at the time of a child's diagnosis of cancer in two-parent versus lone-parent households. J Pediatr Psychol. 2009 Sep;34(8):817-21. Epub 2009 Jan 7. PMID: 19129268; PMCID: PMC2729682.

Jiang X, Gwye Y, McKeown SJ, Bronner-Fraser M, Lutzko C, Lawlor ER. Isolation and characterization of neural crest stem cells derived from in vitro-differentiated human embryonic stem cells. Stem Cells Dev. 2009 Sep;18(7):1059-70. PMID: 19099373. 

Jiang X, Gwye Y, Russell D, Cao C, Douglas D, Hung L, Kovar H, Triche TJ, Lawlor ER. CD133 expression in chemo-resistant Ewing sarcoma cells. BMC Cancer. 2010 Mar 26;10:116. PMID: 20346143; PMCID: PMC2851692.

Johns AL, Oland AA, Katz ER, Sahler OJ, Askins MA, Butler RW, Dolgin MJ. Qualitative analysis of the role of culture in coping themes of Latina and European American mothers of children with cancer. J Pediatr Oncol Nurs. 2009 May-Jun;26(3):167-75. Epub 2009 Apr 27. PMID: 19398713; PMCID: PMC2906121.

Joo J, Christensen L, Warner K, States L, Kang HG, Vo K, Lawlor ER, May WA. GLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors. PLoS ONE. 2009 Oct 27;4(10):e7608. PMID: 19859563; PMCID: PMC2763206.

Kang HG, Jenabi JM, Liu XF, Reynolds CP, Triche TJ, Sorensen PH. Inhibition of the insulin-like growth factor I receptor by epigallocatechin gallate blocks proliferation and induces the death of Ewing tumor cells. Mol Cancer Ther. 2010 May;9(5):1396-407. Epub 2010 Apr 27. PMID: 20423994.

Katzenstein HM, Chang KW, Krailo M, Chen Z, Finegold MJ, Rowland J, Reynolds M, Pappo A, London WB, Malogolowkin M; Children's Oncology Group. Amifostine does not prevent platinum-induced hearing loss associated with the treatment of children with hepatoblastoma: a report of the Intergroup Hepatoblastoma Study P9645 as a part of the Children's Oncology Group. Cancer. 2009 Dec 15;115(24):5828-35. PMID: 19813275; PMCID: PMC2795100.

Keshelava N, Houghton PJ, Morton CL, Lock RB, Carol H, Keir ST, Maris JM, Reynolds CP, Gorlick R, Kolb EA, Wu J, Smith MA. Initial testing (stage 1) of vorinostat (SAHA) by the pediatric preclinical testing program. Pediatr Blood Cancer. 2009 Sep;53(3):505-8. PMID: 19418547; PMCID: PMC2752378.

Khatua S, Dhall G, O'Neil S, Jubran R, Villablanca JG, Marachelian A, Nastia A, Lavey R, Olch AJ, Gonzalez I, Gilles F, Nelson M, Panigrahy A, McComb G, Krieger M, Fan J, Sposto R, Finlay JL. Treatment of primary CNS germinomatous germ cell tumors with chemotherapy prior to reduced dose whole ventricular and local boost irradiation. Pediatr Blood Cancer. 2010 Jul 15;55(1):42-6. PMID: 20222020.

Klemm L, Duy C, Iacobucci I, Kuchen S, von Levetzow G, Feldhahn N, Henke N, Li Z, Hoffmann TK, Kim YM, Hofmann WK, Jumaa H, Groffen J, Heisterkamp N, Martinelli G, Lieber MR, Casellas R, Muschen M. The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia. Cancer Cell. 2009 Sep 8;16(3):232-45. PMID: 19732723; PMCID: PMC2931825.

Ko RH, Ji L, Barnette P, Bostrom B, Hutchinson R, Raetz E, Seibel NL, Twist CJ, Eckroth E, Sposto R, Gaynon PS, Loh ML. Outcome of patients treated for relapsed or refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium study. J Clin Oncol. 2010 Feb 1;28(4):648-54. Epub 2009 Oct 19. PMID: 19841326; PMCID: PMC2815999.

Krieger MD, McComb JG. The role of stereotactic radiotherapy in the management of ependymomas. Childs Nerv Syst. 2009 Oct;25(10):1269-73. Epub 2009 Apr 9. PMID: 19357854.

Labrou NE, Papageorgiou AC, Avramis VI. Structure-function relationships and clinical applications of L-asparaginases. Curr Med Chem. 2010;17(20):2183-95. PMID: 20423302.

Li A, Xing Y, Chan B, Heisterkamp N, Groffen J, Borok Z, Minoo P, Li C. Cell type-specific expression of adenomatous polyposis coli in lung development, injury, and repair. Dev Dyn. 2010 Aug;239(8):2288-97. PMID: 20658693; PMCID: PMC2911649.

London WB, Frantz CN, Campbell LA, Seeger RC, Brumback BA, Cohn SL, Matthay KK, Castleberry RP, Diller L. Phase II randomized comparison of topotecan plus cyclophosphamide versus topotecan alone in children with recurrent or refractory neuroblastoma: a Children's Oncology Group study. J Clin Oncol. 2010 Aug 20;28(24):3808-15. Epub 2010 Jul 26. PMID: 20660830; PMCID: PMC2940398.

Lowe EJ, Sposto R, Perkins SL, Gross TG, Finlay J, Zwick D, Abromowitch M; Children's Cancer Group Study 5941. Intensive chemotherapy for systemic anaplastic large cell lymphoma in children and adolescents: final results of Children's Cancer Group Study 5941. Pediatr Blood Cancer. 2009 Mar;52(3):335-9. PMID: 18985718; PMCID: PMC2769495.

Luna M, Ferrario A, Wong S, Gomer CJ. Identification of MAP kinase pathways involved in COX-2 expression following photofrin photodynamic therapy. Methods Mol Biol. 2010;635:47-63. PMID: 20552339.

Luo P, Yang X, Ying M, Chaudhry P, Wang A, Shimada H, May WA, Adams GB, Mock D, Triche TJ, He Q, Wu L. Retinoid-suppressed phosphorylation of RARalpha mediates the differentiation pathway of osteosarcoma cells. Oncogene. 2010 May 13;29(19):2772-83. Epub 2010 Mar 1. PMID: 20190807.

Mahadeo KM, Dhall G, Ettinger LJ, Kurer CC. Exacerbation of anthracycline-induced early chronic cardiomyopathy with ATRA: role of B-type natriuretic peptide as an indicator of cardiac dysfunction. Pediatr Hematol Oncol. 2010 Mar;32(2):134-6. PMID: 20098333.

Mahadeo KM, Dhall G, Panigrahy A, Lastra C, Ettinger LJ. Subacute methotrexate neurotoxicity and cerebral venous sinus thrombosis in a 12-year-old with acute lymphoblastic leukemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: homocysteine-mediated methotrexate neurotoxicity via direct endothelial injury. Pediatr Hematol Oncol. 2010 Feb;27(1):46-52. PMID: 20121554

Mascarenhas L. Difficulties diagnosing spinal subdural hemorrhage in a hypo-coagulated patient due to simultaneous symptomatic subdural cranial hemorrhage. Eur Spine J. 2009 Jul;18(Suppl 2):217-9. Epub 2008 Dec 11. PMID: 19082640; PMCID: PMC2899568.

Massimino M, Cohen KJ, Finlay JL. Is there a role for myeloablative chemotherapy with autologous hematopoietic cell rescue in the management of childhood high-grade astrocytomas? Pediatr Blood Cancer. 2010 Apr;54(4):641-3. doi: 10.1002/pbc.22375. Epub 2010 Feb 9.

Matthay KK, Quach A, Huberty J, Franc BL, Hawkins RA, Jackson H, Groshen S, Shusterman S, Yanik G, Veatch J, Brophy P, Villablanca JG, Maris JM. Iodine-131--metaiodobenzylguanidine double infusion with autologous stem-cell rescue for neuroblastoma: a new approaches to neuroblastoma therapy phase I study. J Clin Oncol. 2009 Mar 1;27(7):1020-5. Epub 2009 Jan 26.

Matthay KK, Reynolds CP, Seeger RC, Shimada H, Adkins ES, Haas-Kogan D, Gerbing RB, London WB, Villablanca JG. Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: a Children's Oncology Group study. J Clin Oncol. 2009 Mar 1;27(7):1007-13. Epub 2009 Jan 26. PMID: 19171716; PMCID: PMC2738615.

Meeske KA, Siegel SE, Gilsanz V, Bernstein L, Nelson MB, Sposto R, Weaver FA, Lavey RS, Mack MP, Nelson MD Jr. Premature carotid artery disease in pediatric cancer survivors treated with neck irradiation. Pediatr Blood Cancer. 2009 Oct;53(4):615-21. PMID: 19533651.

Meeske KA, Sullivan-Halley J, Smith AW, McTiernan A, Baumgartner KB, Harlan LC, Bernstein L. Risk factors for arm lymphedema following breast cancer diagnosis in Black women and White women. Breast Cancer Res Treat. 2009 Jan;113(2):383-91. Epub 2008 Feb 24. PMID: 18297429.

Messinger Y, Gaynon P, Raetz E, Hutchinson R, Dubois S, Glade-Bender J, Sposto R, van der Giessen J, Eckroth E, Bostrom BC. Phase I study of bortezomib combined with chemotherapy in children with relapsed childhood acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia (TACL) consortium. Pediatr Blood Cancer. 2010 Aug;55(2):254-9. PMID: 20582937.

Meyers RL, Rowland JR, Krailo M, Chen Z, Katzenstein HM, Malogolowkin MH. Predictive power of pretreatment prognostic factors in children with hepatoblastoma: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2009 Dec;53(6):1016-22. PMID: 19588519.

Mittelman SD, Gilsanz P, Mo AO, Wood J, Dorey F, Gilsanz V. Adiposity predicts carotid intima-media thickness in healthy children and adolescents. J Pediatr. 2010 Apr;156(4):592-7.e2. Epub 2009 Dec 14. PMID: 20004913.

Mittelman SD, Klier K, Braun S, Azen C, Geffner ME, Buchanan TA. Obese adolescents show impaired meal responses of the appetite-regulating hormones ghrelin and PYY. Obesity (SilverSpring). 2010 May;18(5):918-25. Epub 2010 Jan 21. PMID: 20094039; PMCID: PMC2940837.

Molyneux SD, Di Grappa MA, Beristain AG, McKee TD, Wai DH, Paderova J, Kashyap M, Hu P, Maiuri T, Narala SR, Stambolic V, Squire J, Penninger J, Sanchez O, Triche TJ, Wood GA, Kirschner LS, Khokha R. Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice. J Clin Invest. 2010 Sep 1;120(9):3310-25. doi: 10.1172/JCI42391. Epub 2010 Aug 9. PMID: 20697156.

Moreno L, Pollack IF, Duffner PK, Geyer JR, Grill J, Massimino M, Finlay JL, Zacharoulis S. Utility of cerebrospinal fluid cytology in newly diagnosed childhood ependymoma. J Pediatr Hematol Oncol. 2010 Aug;32(6):515-8. PMID: 20463607.

Muni RH, Kohly RP, Sohn EH, Lee TC. Hand-held spectral domain optical coherence tomography finding in shaken-baby syndrome. Retina. 2010 Apr;30(Suppl 4):S45-S50. PMID: 20386092.

Nachman JB, La MK, Hunger SP, Heerema NA, Gaynon PS, Hastings C, Mattano LA Jr, Sather H, Devidas M, Freyer DR, Steinherz PG, Seibel NL. Young adults with acute lymphoblastic leukemia have an excellent outcome with chemotherapy alone and benefit from intensive postinduction treatment: a report from the Children's Oncology Group. J Clin Oncol. 2009 Nov 1;27(31):5189-94. Epub 2009 Oct 5. PMID: 19805689.

Nahar R, Muschen M. Pre-B cell receptor signaling in acute lymphoblastic leukemia. Cell Cycle. 2009 Dec;8(23):3874-7. Epub 2009 Dec 9. PMID: 19901533.

Nicolino M, Byrne B, Wraith JE, Leslie N, Mandel H, Freyer DR, Arnold GL, Pivnick EK, Ottinger CJ, Robinson PH, Loo JC, Smitka M, Jardine P, Tato L, Chabrol B, McCandless S, Kimura S, Mehta L, Bali D, Skrinar A, Morgan C, Rangachari L, Corzo D, Kishnani PS. Clinical outcomes after long-term treatment with alglucosidase alfa in infants and children with advanced Pompe disease. Genet Med. 2009 Mar;11(3):210-9. PMID: 19287243.

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Parameswaran R, Muschen M, Kim YM, Groffen J, Heisterkamp N. A functional receptor for B-cell-activating factor is expressed on human acute lymphoblastic leukemias. Cancer Res. 2010 Jun 1;70(11):4346-56. Epub 2010 May 11. PMID: 20460528; PMCID: PMC2880197.

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Paul Chan RV, Williams SL, Yonekawa Y, Weissgold DJ, Lee TC, Chiang MF. Accuracy of retinopathy of prematurity diagnosis by retinal fellows. Retina. 2010 Jun;30(6):958-65. PMID: 20168274; PMCID: PMC2884082.

Pique-Regi R, Ortega A, Asgharzadeh S. Joint estimation of copy number variation and reference intensities on multiple DNA arrays using GADA. Bioinformatics. 2009 May 15;25(10):1223-30. Epub 2009 Mar 10. PMID: 19276152. PMCID: PMC2732310.

Pollack IF, Hamilton RL, Sobol RW, Nikiforova MN, Nikiforov YE, Lyons-Weiler MA, LaFramboise WA, Burger PC, Brat DJ, Rosenblum MK, Gilles FH, Yates AJ, Zhou T, Cohen KJ, Finlay JL, Jakacki RI; Children's Oncology Group. Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2010 Dec 1;55(6):1066-71. PMID: 20589656.

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Qazi S, Uckun FM. Gene expression profiles of infant acute lymphoblastic leukaemia and its prognostically distinct subsets. Br J Haematol. 2010 Jun;149(6):865-73. Epub 2010 Apr 4. PMID: 20377589.

Richter GM, Sun G, Lee TC, Chan RV, Flynn JT, Starren J, Chiang MF. Speed of telemedicine vs ophthalmoscopy for retinopathy of prematurity diagnosis. Am J Ophthalmol. 2009 Jul;148(1):136-42.e2. Epub 2009 Apr 18. PMID: 19376496.

Robison NJ, Dawlabani N, Lastra CR, Dhall G. Cerebral sinus thrombosis in a child with active ulcerative colitis and factor V Leiden. Pediatr Blood Cancer. 2009 Jul;52(7):867-9. PMID: 19260108.

Rosol M, Harutyunyan I, Xu J, Melendez E, Smbatyan G, Finlay JL, Krieger MD, Gonzalez-Gomez I, Reynolds CP, Nelson MD, Erdreich-Epstein A, Bluml S. Metabolism of orthotopic mouse brain tumor models. Mol Imaging. 2009 Jul-Aug;8(4):199-208. PMID: 19728974.

Rovelo MO, Kim R, Mascarenhas L, Hammoudeh J, Urata MM. Recurrent and refractory giant cell tumor of the jaw. J Craniofac Surg. 2009 Nov;20(6):2245-8. PMID: 19934683.

Ruccione K. The legacy of pediatric oncology nursing in advancing survivorship research and clinical care. J Pediatr Oncol Nurs. 2009 Sep-Oct;26(5):255-65. PMID: 19837956.

Sands SA, Oberg JA, Gardner SL, Whiteley JA, Glade-Bender JL, Finlay JL. Neuropsychological functioning of children treated with intensive chemotherapy followed by myeloablative consolidation chemotherapy and autologous hematopoietic cell rescue for newly diagnosed CNS tumors: an analysis of the Head Start II survivors. Pediatr Blood Cancer. 2010 Mar;54(3):429-36. PMID: 20052775.

Sands SA, Pasichow KP, Weiss R, Garvin J, Gardner S, Dunkel IJ, Finlay JL. Quality of life and behavioral follow-up study of Head Start I pediatric brain tumor survivors. J Neurooncol. 2011 Jan;101(2):287-95. Epub 2010 Jun 6. PMID: 20526792.

Schultz KR, Bowman WP, Aledo A, Slayton WB, Sather H, Devidas M, Wang C, Davies SM, Gaynon PS, Trigg M, Rutledge R, Burden L, Jorstad D, Carroll A, Heerema NA, Winick N, Borowitz MJ, Hunger SP, Carroll WL, Camitta B. Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a Children's Oncology Group study. J Clin Oncol. 2009 Nov 1;27(31):5175-81. Epub 2009 Oct 5. PMID: 19805687; PMCID: PMC2773475.

Schwartz CL, Constine LS, Villaluna D, London WB, Hutchison RE, Sposto R, Lipshultz SE, Turner CS, deAlarcon PA, Chauvenet A. A risk-adapted, response-based approach using ABVE-PC for children and adolescents with intermediate- and high-risk Hodgkin lymphoma: the results of P9425. Blood. 2009 Sep 3;114(10):2051-9. Epub 2009 Jul 7. PMID: 19584400; PMCID: PMC2744567.

Serowka K, Chiu Y, Gonzalez I, Gilles F, McComb G, Krieger M, Dhall G, Britt B, Ji L, Sposto R, Finlay JL. Central nervous system (CNS) tumors in the first six months of life: the Children's Hospital Los Angeles experience, 1979-2005. Pediatr Hematol Oncol. 2010 Mar;27(2):90-102. PMID: 20201690.

Sherman CB, Ali-Nazir A, Gonzales-Gomez I, Finlay JL, Dhall G. Primary mixed glioneuronal tumor of the central nervous system in a patient with noonan syndrome: a case report and review of the literature. J Pediatr Hematol Oncol. 2009 Jan;31(1):61-4. PMID: 19125092.

Shusterman SS, London WB, Gillies SD, Hank JA, Voss SD, Seeger RC, Reynolds CP, Kimball J, Albertini MR, Wagner B, Gan J, Eickhoff J, DeSantes KB, Cohn SL, Hecht T, Gadbaw B, Reisfeld RA, Maris JM, Sondel PM. Antitumor activity of hu14.18-IL2 in patients with relapsed/refractory neuroblastoma: a Children's Oncology Group (COG) phase II study. J Clin Oncol. 2010 Nov 20;28(33):4969-75. Epub 2010 Oct 4. PMID: 20921469.

Si SJ, Khatua S, Dhall G, Nelson MD, Gonzalez-Gomez I, Finlay JL. Regression of primary central nervous system germinoma after dexamethasone administration: a case report. Pediatr Hematol Oncol. 2010 Apr;27(3):237-43. PMID: 20367268.

Song HR, Gonzalez-Gomez I, Suh GS, Commins DL, Sposto R, Gilles FH, Deneen B, Erdreich-Epstein A. Nuclear factor IA is expressed in astrocytomas and is associated with improved survival. Neuro Oncol. 2010 Feb;12(2):122-32. Epub 2010 Jan 25. PMID: 20150379; PMCID: PMC2940580.

Song L, Asgharzadeh S, Salo J, Engell K, Wu HW, Sposto R, Ara T, Silverman AM, DeClerck YA, Seeger RC, Metelitsa LS. Valpha24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages. J Clin Invest. 2009 Jun;119(6):1524-36. PMID: 19411762; PMCID: PMC2689106.

Souweidane MM, Krieger MD, Weiner HL, Finlay JL. Surgical management of primary central nervous system germ cell tumors: proceedings from the Second International Symposium on Central Nervous System Germ Cell Tumors. J Neurosurg Pediatr. 2010 Aug;6(2):125-30. PMID: 20672932.

Sposto R. Commentary on paper, 'cancer survival analysis'. Surg Oncol. 2010 Jun;19(2):59-60; discussion 61. Epub 2010 May 15. PMID: 20471825.

Sposto R, Gaynon PS. An adjustment for patient heterogeneity in the design of two-stage phase II trials. Stat Med. 2009 Sep 10;28(20):2566-79. PMID: 19521973.

Spreafico F, Pritchard JK, Malogolowkin MH, Bergeron C, Hale J, de Kraker J, Dallorso S, Acha T, de Camargo B, Dome JS, Graf N. Treatment of relapsed Wilms tumors: lessons learned. Expert Rev Anticancer Ther. 2009 Dec;9(12):1807-15. PMID: 19954292.

Stork LC, Matloub Y, Broxson E, La M, Yanofsky R, Sather H, Hutchinson R, Heerema NA, Sorrell AD, Masterson M, Bleyer A, Gaynon PS. Oral 6-mercaptopurine versus oral 6-thioguanine and veno-occlusive disease in children with standard-risk acute lymphoblastic leukemia: report of the Children's Oncology Group CCG-1952 clinical trial. Blood. 2010 Apr 8;115(14):2740-8. Epub 2010 Feb 1. PMID: 20124218; PMCID: PMC2854423.

Taggart DR, Han MM, Quach A, Groshen S, Ye W, Villablanca JG, Jackson HA, Mari Aparici C, Carlson D, Maris J, Hawkins R, Matthay KK. Comparison of iodine-123 metaiodobenzylguanidine (MIBG) scan and [18F]-fluorodeoxyglucose positron emission tomography to evaluate response after iodine-131 MIBG therapy for relapsed neuroblastoma. J Clin Oncol. 2009 Nov 10;27(32):5343-9. Epub 2009 Oct 5. PMID: 19805691; PMCID: PMC2773221.

Terterov S, Krieger MD, Bowen I, McComb JG. Evaluation of intracranial cerebrospinal fluid cytology in staging pediatric medulloblastomas, supratentorial primitive neuroectodermal tumors, and ependymomas. J Neurosurg Pediatr. 2010 Aug;6(2):131-6. PMID: 20672933.

Thyparampil PJ, Park Y, Martinez-Perez ME, Lee TC, Weissgold DJ, Berrocal AM, Chan RV, Flynn JT, Chiang MF. Plus disease in retinopathy of prematurity: quantitative analysis of vascular change. Am J Ophthalmol. 2010 Oct;150(4):468-475.e2. PMID: 20643397; PMCID: PMC2945436.

Trageser D, Iacobucci I, Nahar R, Duy C, von Levetzow G, Klemm L, Park E, Schuh W, Gruber T, Herzog S, Kim YM, Hofmann WK, Li A, Storlazzi CT, Jack HM, Groffen J, Martinelli G, Heisterkamp N, Jumaa H, Muschen M. Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function. J Exp Med. 2009 Aug 3;206(8):1739-53. Epub 2009 Jul 20. PMID: 19620627; PMCID: PMC2722172.

Uckun FM, Dibirdik I, Qazi S. Augmentation of the antileukemia potency of total-body irradiation (TBI) by a novel P-site inhibitor of spleen tyrosine kinase (SYK). Radiat Res. 2010 Oct;174(4):526-31. PMID: 20731589.

Uckun FM, Dibirdik I, Qazi S. Prevention of UVB-induced skin inflammation, genotoxicity, and photocarcinogenesis in mice by WHI-P131, a dual-function inhibitor of Janus kinase 3 and EGF receptor kinase. Arzneimittelforschung. 2010;60(4):218-25. PMID: 20486473.

Uckun FM, Dibirdik I, Qazi S, Yiv S. Therapeutic nanoparticle constructs of a JAK3 tyrosine kinase inhibitor against human B-lineage ALL cells. Arzneimittelforschung. 2010;60(4):210-7. PMID: 20486472.

Uckun FM, Ek RO, Jan ST, Chen CL, Qazi S. Targeting SYK kinase-dependent anti-apoptotic resistance pathway in B-lineage acute lymphoblastic leukaemia (ALL) cells with a potent SYK inhibitory pentapeptide mimic. Br J Haematol. 2010 May;149(4):508-17. Epub 2010 Feb 11. PMID: 20151979.

Uckun FM, Ozer Z, Qazi S, Tuel-Ahlgren L, Mao C. Polo-like-kinase 1 (PLK1) as a molecular target to overcome SYK-mediated resistance of B-lineage acute lymphoblastic leukaemia cells to oxidative stress. Br J Haematol. 2010 Mar;148(5):714-25. Epub 2009 Nov 12. PMID: 19912216.

Uckun FM, Qazi S, Ma H, Tuel-Ahlgren L, Ozer Z. STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2902-7. Epub 2010 Jan 29. PMID: 20133729; PMCID: PMC2840303.

van Doorninck JA, Ji L, Schaub B, Shimada H, Wing MR, Krailo MD, Lessnick SL, Marina N, Triche TJ, Sposto R, Womer RB, Lawlor ER. Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group. J Clin Oncol. 2010 Apr 20;28(12):1989-94. Epub 2010 Mar 22. PMID: 20308669; PMCID: PMC2860404.

Wagner LM, Villablanca JG, Stewart CF, Crews KR, Groshen S, Reynolds CP, Park JR, Maris JM, Hawkins RA, Daldrup-Link HE, Jackson HA, Matthay KK. Phase I trial of oral irinotecan and temozolomide for children with relapsed high-risk neuroblastoma: a new approach to neuroblastoma therapy consortium study. J Clin Oncol. 2009 Mar 10;27(8):1290-6. Epub 2009 Jan 26. PMID: 19171709; PMCID: PMC2667827.

Wang A, Alimova IN, Luo P, Jong A, Triche TJ, Wu L. Loss of CAK phosphorylation of RAR{alpha} mediates transcriptional control of retinoid-induced cancer cell differentiation. FASEB J. 2010 Mar;24(3):833-43. Epub 2009 Nov 16. PMID: 19917671; PMCID: PMC2830139.

Wells EM, Khademian ZP, Walsh KS, Vezina G, Sposto R, Keating RF, Packer RJ. Postoperative cerebellar mutism syndrome following treatment of medulloblastoma: neuroradiographic features and origin. J Neurosurg Pediatr. 2010 Apr;5(4):329-34. PMID: 20367335.

Williams SL, Wang L, Kane SA, Lee TC, Weissgold DJ, Berrocal AM, Rabinowitz D, Starren J, Flynn JT, Chiang MF. Telemedical diagnosis of retinopathy of prematurity: accuracy of expert versus non-expert graders. Br J Ophthalmol. 2010 Mar;94(3):351-6. Epub 2009 Dec 2. PMID: 19955195.

Wu CC, Asgharzadeh S, Triche TJ, D'Argenio DZ. Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning. Bioinformatics. 2010 Mar 15;26(6):807-13. Epub 2010 Feb 4. PMID: 20134029; PMCID: PMC2832827.

Xiong G, Husseiny MI, Song L, Erdreich-Epstein A, Shackleford GM, Seeger RC, Jackel D, Hensel M, Metelitsa LS. Novel cancer vaccine based on genes of Salmonella pathogenicity island 2. Int J Cancer. 2010 Jun 1;126(11):2622-34. PMID: 19824039.

Xu J, Millard M, Ren X, Cox OT, Erdreich-Epstein A. c-Abl mediates endothelial apoptosis induced by inhibition of integrins alphavbeta3 and alphavbeta5 and by disruption of actin. Blood. 2010 Apr 1;115(13):2709-18. Epub 2010 Feb 2. PMID: 20124512; PMCID: PMC2852370.

Xu XL, Fang Y, Lee TC, Forrest D, Gregory-Evans C, Almeida D, Liu A, Jhanwar SC, Abramson DH, Cobrinik D. Retinoblastoma has properties of a cone precursor tumor and depends upon cone-specific MDM2 signaling. Cell. 2009 Jun 12;137(6):1018-31. PMID: 19524506.

Yu AL, Gilman AL, Ozkaynak MF, London WB, Kreissman SG, Chen HX, Smith M, Anderson B, Villablanca JG, Matthay KK, Shimada H, Grupp SA, Seeger R, Reynolds CP, Buxton A, Reisfeld RA, Gillies SD, Cohn SL, Maris JM, Sondel PM; Children's Oncology Group. Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma. N Engl J Med. 2010 Sep 30;363(14):1324-34. PMID: 20879881.

Yi SJ, Groffen J, Heisterkamp N. Transglutaminase 2 regulates the GTPase-activating activity of Bcr. J Biol Chem. 2009 Dec 18;284(51):35645-51. PMID: 19840940; PMCID: PMC2790995.

Yun JP, Behan JW, Heisterkamp N, Butturini A, Klemm L, Ji L, Groffen J, Muschen M, Mittelman SD. Diet-induced obesity accelerates acute lymphoblastic leukemia progression in two murine models. Cancer Prev Res(Phila). 2010 Oct;3(10):1259-64. Epub 2010 Sep 7. PMID: 20823291; PMCID: PMC2955776.

Zada G, Ditty B, McNatt SA, McComb JG, Krieger MD. Surgical treatment of rathke cleft cysts in children. Neurosurgery. 2009 Jun;64(6):1132-7 author reply 1037-8. PMID: 19487893.

Zada G, McNatt SA, Gonzalez-Gomez I, McComb JG. Anaplastic intraventricular oligodendroglioma: case report and review of the literature. Surg Neurol. 2009 Jun;71(6):693-700. Epub 2008 Mar 4. PMID: 18291495.