 Mark S. Borchert, MD, is director of the Eye Birth Defects Institute and Eye Technology Institute in the Vision Center at Children's Hospital Los Angeles, where he is head of its Division of Ophthalmology. Dr. Borchert is associate professor of clinical ophthalmology and neurology at the Keck School of Medicine of the University of Southern California. After receiving his medical degree at Baylor College of Medicine, he completed his residency at the Doheny Eye Institute University of Southern California, and a fellowship in neuro-ophthalmology at the Massachusetts Eye & Ear Infirmary, Harvard University.
Dr. Borchert, who has been listed in “Best Doctors in America,” also has received honors from the Pan American Association of Opthalmology, the American Academy of Ophthalmology, and Society of Heed Fellows, as well as several teaching awards from the Keck School of Medicine. He directs the world’s largest study into optic nerve hypoplasia, now the single leading cause of blindness in infants in the United States and Europe.
Another area of Dr. Borchert’s research is the development of better diagnostic and treatment tools, in particular the pioneering use of spectroscopy to measure glucose levels in the eye.
Honors and Awards
- 2010 Pasadena Magazine Top Doctors Award
- 2010 Los Angeles Magazine Super Doctors Award
- 2009 Best Doctors in America Award
- 2009 America's Top Doctors, Eighth Edition
- 2009 LA Times Magazine Best Doctors in Southern California
- 2008 Pasadena Magazine Top Doctors Award
- 2008 America's Top Doctors Award, Seventh Edition
- 2006 Best Doctors in America Award
- 2006 America’s Top Doctors, Sixth Edition
- 2002 American Academy of Ophthalmology Achievement Award
- 1991-94, 96, 99, 01 - Resident Teaching Award - USC School of Medicine
- 1994-94 - Senior Resident Teaching Award - USC School of Medicine - Department of Ophthalmology
Other Bios
Major Areas of Research Interest
Dr. Borchert’s research primarily focuses on the development of the optic nerve and its retinotopic connections in the tectum (part of the midbrain) and thalamus (part of the forebrain). He is interested in the role that inaccurate or inadequate development of these connections plays in the pathogenesis of optic nerve hypoplasia.
Research In Progress
- Epidemiology of optic nerve hypoplasia
- Clinical risk factors of optic nerve hypoplasia
A study headed by Mark S. Borchert, MD is designed to provide preliminary data about the factors involved in formation of ONH prior to birth. This study may improve physicians’ ability to provide earlier identification and treatment of ONH. In addition, a greater understanding of prenatal risk factors may allow physicians to prevent this disease in the future. For more information or to partake in the study, click here.
Recent Published Research
Determination of glucose in human aqueous humor using Raman spectroscopy and designed-solution calibration.
Pelletier CC, Lambert JL, Borchert M.
Endocrinological and Auxological Abnormalities in Young Children With Optic Nerve Hypoplasia: A Prospective Study
Ahmad T, Garcia-Filion P, Borchert M, Kaufman F, Burkett L, Geffner M
Etiology of eyelid retraction in children: a retrospective study.
Stout AU, Borchert M.
Glucose determination in human aqueous humor with Raman spectroscopy.
Lambert JL, Pelletier CC, Borchert M.
Determination of glucose in human aqueous humor using Raman spectroscopy and designed-solution calibration.
Pelletier CC, Lambert JL, Borchert M.
Independence of optokinetic nystagmus asymmetry and binocularity in infantile esotropia.
Aiello A, Wright KW, Borchert M.
Neuroradiographic, Endocrinologic, and Ophthalmic Correlates of Adverse Developmental Outcomes in Children With Optic Nerve Hypoplasia: A Prospective Study
Pediatrics, Mar 2008; 121: e653 - e659.
Pamela Garcia-Filion, MPH, Karen Epport, PhD, Marvin Nelson, MDd, Colleen Azen, MS, Mitchell E. Geffner, MD, Cassandra Fink, MPH and Mark Borchert, MD
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Optic Nerve Hypoplasia in North America: A Re-Appraisal of Perinatal Risk Factors
Acta Ophthalmologica 2008
Pamela Garcia-Filion, MPH, Cassandra Fink, MPH, Mitchell E. Geffner, MD, and Mark Borchert, MD
Testability of the Retinomax Autorefractor and IOLMaster in Preschool Children The Multi-ethnic Pediatric Eye Disease Study.
Borchert M, Wang Y, Tarczy-Hornoch K, Cotter S, Deneen J, Azen S, Varma R; MEPEDS Study Group.
The Syndrome of Optic Nerve Hypoplasia
Current Neurology and Neuroscience Reports 2008 8: 395-403
Borchert, MD, Garcia-Filion, MPH
Publications
Neuroradiographic, Endocrinological, and Ophthalmic Correlates of Adverse Developmental Outcomes in Children with Optic Nerve Hypoplasia: A Prospective Study.
Garcia-Filion, P, Epport K, Nelson M, Azen C, Geffner M, Fink C, Borchert M. Pediatrics 2008; 121:e653-9
Optic Nerve Hypoplasia in North America: A Reappraisal of Perinatal Risk Factors
Garcia-Filion P, Fink C, Geffner M, Borchert M. Acta Ophthalmol.
Long-term Outcomes of Pediatric Ocular Myasthenia Gravis.
Ortiz S, Borchert M.
Clinical assessment, optic disk measurements, and visual-evoked potential in optic nerve hypoplasia.
Borchert M, McCulloch D, Rother C, Stout AU.
Independence of optokinetic nystagmus asymmetry and binocularity in infantile esotropia.
Aiello A, Wright KW, Borchert M.
Etiology of eyelid retraction in children: a retrospective study.
Stout AU, Borchert M.
Papilledema. In Retinal Imaging.
Mosby Elsevier, Philadelphia, PA, 2006
Non-Organic Vision Loss. In Neuro-Ophthalmology.
Levine and Arnold, 2005.
Principles and techniques of examination of the ocular motor system.
In Walsh and Hoyt’s Clinical Neuro-Ophthalmology: 6th Ed., NR Miller, and NJ Newman, eds., Baltimore, Williams & Wilkins, 2004.
Ying S: Neurodegenerative Conditions of Ophthalmic Importance.
In Pediatric Ophthalmology and Strabismus, 2nd Ed., P. H. Spiegel and KW Wright, eds., New York, Springer-Verlag, Inc., 2002.
Clinician’s Corner: Diagnosis and Management of the Infant Who Does Not See.
In Focal Points: Clinical Modules for Ophthalmologists. Wright KW, ed. American Academy of Ophthalmology, San Francisco, Vol XVI, No. 12, pp 11-14, 1998.
Diseases of the Ocular Muscles. In Principles and Practice of Ophthalmology.
2nd Ed., DM Albert, FA Jakobiec, eds., Philadelphia, WB Saunders Company, 1998.
Principles and techniques of examination of the ocular motor system.
Walsh and Hoyt’s Clinical Neuro-Ophthalmology: 5th Ed., NR Miller, and NJ Newman, eds., Baltimore, Williams & Wilkins, 1998.
Vascular anatomy of the visual system.
Ophthalmology Clinics of North America 9:327 - 337 W.B. Saunders 1996.
Evaluation of Childhood Nystagmus.
Pediatric Ophthalmology and Strabismus, KW Wright, ed., Chicago, Mosby Co., 1995.
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