The Eye Birth Defects Institute in The Vision Center at Children's Hospital Los Angeles treats and studies a full spectrum of congenital diseases that result in anatomic abnormalities of the eye and optic nerve, including optic nerve hypoplasia, the leading cause of blindness in infants in the United States. The Eye Birth Defects Institute is the leading research center in the epidemiology and management of this and other devastating eye birth defects.
The Institute is known worldwide for its extensive research program and successful outcomes for children with extraordinary eye disorders. Under the direction of Mark S. Borchert, MD, the Eye Birth Defects Institute collaborates with other organizations and medical professionals in a quest to find answers for complex optic nerve disorders and other pediatric eye conditions.
Health Forum Interview
Optic Nerve Hypoplasia (ONH) Leadership
The Eye Birth Defects Institute has the largest study in the world on ONH, with more than 200 subjects enrolled in an ongoing prospective study to determine the prenatal and clinical risk factors for adverse outcomes in children.
ONH occurs when a child’s optic nerves fail to develop fully during early pregnancy, resulting in reduced vision or blindness. ONH is now the foremost single cause of blindness and visual impairment in infants in the United States.