Childrens Center for Cancer & Blood Diseases
The Childrens Center for Cancer and Blood Diseases pioneered treatments now used as the standard for acute leukemia, the most common childhood cancer.
Heart Institute
The Heart Institute performed the first pediatric heart surgery on the West Coast in 1939.
Childrens Brain Center
The Childrens Brain Center has changed the world of brain research for children with the development of a magnetic resonance-compatible incubator, making Childrens Hospital Los Agneles the first in the world to perform functional magnetic resonance imaging (fMRI) on even the tiniest babies. This powerful tool, which allows researchers to study how the developing brain processes information, will advance the understanding of brain function in both children and adults.
The Saban Research Institute
Researchers at The Saban Research Institute:
- pioneered a treatment that improved the survival rate of children with neuroblastoma from 15% to 55% (treatment combines bone marrow transplantation, chemotherapy and retinoic acid)
- developed an innovative laser/chemotherapy treatment for retinoblastoma that is considered the most significant therapeutic advance in a quarter-century
- performed the world's first transfer of a healthy gene into the umbilical cord blood cells of a newborn to correct a genetic defect detected in utero in a baby with Severe Combined Immunodeficiency Disease, known in common parlance as “bubble baby” disease
- conducted the world’s first gene therapy clinical trial for children infected with HIV-1
- identified molecules that interact with genes to trigger the growth of lung stem cells into lung tissue, becoming the first to grow lung tissue in the laboratory
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