Basic and Translational Research Program
Basic researchers at The Saban Research Institute explore the molecular underpinnings of disease to translate this knowledge into new tools for diagnosis and treatment. In our vigorous clinical research program, we participate in more than 121 active clinical trials, including the Children’s Oncology Group (COG), a cooperative group for childhood cancer. Our interests include:
The Center houses the USC-CHLA Institute for Pediatric Clinical Research, where investigations in developmental therapeutics pursue promising cancer drugs. Childrens Hospital also operates an NIH-designated pediatric site of a General Clinical Research Center, part of the USC GCRC.
Research LeadershipOur doctors and scientists are recipients of multiple grants from the NIH, as well as from private philanthropy and industry. We serve in key leadership roles in the COG, which gives our patients access to the best and newest therapies anywhere. In addition, our nationally recognized nursing research program is headed by the chair of the COG’s nursing committee. Our Biostatistics and Informatics Center is led by the former group statistician of the COG. We maintain several reference laboratories for the COG and other clinical assays, which are federally certified under the Clinical Laboratory Improvement Amendments, assuring accuracy, reliability and timeliness of patient test results. Blood DiseasesWe collaborate with experts in biomedical engineering, biophysics and hematology within our NIH-funded Basic and Translational Research Program (BTRP) studying sickle cell disease. The BTRP involves physicians from Childrens Hospital, as well as faculty from the Keck School of Medicine and the Viterbi School of Engineering at USC. In addition, our hematology researchers conduct pioneering research into the measurement and management of iron for patients with blood disease, as well as the basic pathology of sickle cell disease. |













