Jeffrey Upperman, M.D.Title:Director, Trauma Program Program Director, PDRTC
Department:General Pediatric Surgery
Primary Specialty:Pediatric Surgery
Secondary Specialty:
Research Interests:Necrotizing Enterocolitis; Nitric Oxide in Gut Barrier Failure; Pediatric Trauma; Pediatric Disaster Preparedness. RESEARCH IN PROGRESS: The Role of Nitric Oxide and Reactive Nitrogen Species in Gut Barrier Failure; Genomics of Necrotizing Enterocolitis; Cytokine Gene Polymorphisms in Necrotizing Enterocolitis; Mathematical Modeling in Necrotizing Enterocolitis; Pediatric Disaster Preparedness in Los Angeles County
Clinical Interests:Trauma, Disaster Preparedness;
Injury Prevention
Certification:Surgery: American Board of Surgery; Pediatric Surgery: American Board of Surgery
Medical School:New Jersey Medical School
Internship:University Hospital, New Jersey Medical School, General Surgery
Residency:University Hospital, New Jersey Medical School, General Surgery; Administrative Chief Resident.
Fellowship:Children's Hospital of Pittsburgh, Pediatric Surgery
Medical Memberships:American College of Surgeons; American Academy of Pediatrics; American Pediatric Surgical Association; Allegheny County Medical Society (ACMS), 2000-2005; American College of Surgeons (ACS), Southwestern Pennsylvania Chapter, 2000-2005; American College of Surgeons (ACS), Southern California Chapter, 2006- present; Pittsburgh Surgical Society, 2003-2005
Years on Staff:3
Physician Type:CHLA
Recent Publications:Zamora, R.; Grishin, A.; Wong, C.; Boyle, P.; Wang, J.; Hackam, D.; Upperman, JS, Tracey, K. J.; Ford, H. R. Carbon monoxide protects against the development of experimental necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol 2005;289(3):G607-13; Grishin AV, Wang J, Potoka DA, Hackam DJ, Upperman JS, Boyle P, Zamora R, Ford HR. Lipopolysaccharide induces cyclooxygenase-2 in intestinal epithelium via a noncanonical p39 MAPK pathway. J Immunol 2006(Jan 1);176 (1):580-8; Potoka D, McClain R, Upperman JS. Pediatric cystadenoma of the mesocolon. Pediatr Surg. 2006 Jan;41(1):e63-4; Wang KS, Ford HR, Upperman JS. Metabolic Response to Stress in the Surgical Neonates.
Neoreviews 2006 7: e410-e418; Cetin S, Leaphart C, Li J, Ischenko I, Hayman M, Upperman JS, Zamora R, Watkin SK, Ford HR, Wang JH, Hackam DJ. Nitric Oxide Inhibits Enterocyte Migration through Activation of RhoA-GTPase in a SHP-2 Dependent Manner. Am J Physiol Gastrointest Liver Physiol. 2007 Feb 1; [Epub ahead of print] PMID: 17272518; Upperman JS, Camerini V, Lugo B, Yotov I, Sullivan J, Rubin J. Clermont G, Zamora R, Ermentrout GB, Ford HR, Vodvotz Y; Mathematical Modeling in Necrotizing Enterocolitis- A New look at an ongoing problem. Journal of Pediatric Surgery. 2007 March; 42(3): 445-53; Sun Jianping, Liu Yi-Hsin, Chen Hui, Nguyen Manuel, Mishina Yuji, Upperman JS, Ford, HR, Shi Wei. Deficient Alk-3 mediated BMP signaling causes prenatal omphalocele-like defect. Biochemical and Biophysical Research Communications 360 (2007) 238-243.
Additional Publications:
 Excellence is the only option...
Contact Information:Phone: (323) 361-2322Fax: (323) 361-3534 Address: CHLA, Pediatric Surgery #100 Los Angeles CA 90027 |
