Research Seminar: “Suppression of IgE-mediated Allergy by Oral Immunotherapy”

Speaker: Wayne G. Shreffler, MD, PhD, Director, Food Allergy Center, Massachusetts General Hospital, Division Chief, Pediatric Allergy and Immunology, MassGeneral Hospital of Children
Principal Investigator, Center for Immunology and Inflammatory Diseases, Associate Professor of Pediatrics, Harvard Medical School
Talk Summary: The phenotypic heterogeneity of IgE-mediated food allergy is often overlooked in both current clinical practice, and just as importantly, in the context of clinical and translational research. Developing the collaborative infrastructure and methods for carefully phenotyping these patients will enrich our understanding from population and interventional studies of food allergies. Here we will show how the careful immune and clinical phenotyping of food allergic patients, before and after oral immunotherapy, reveals a spectrum of disease that may have bearing on the course of disease during its natural history and response to interventions. Understanding this phenotypic diversity will enrich population-based studies and possibly lead to relatively rapid improvements in diagnostic and prognostic accuracy for patients.
Hosted by Jonathan Tam, MD, FAAAAI FACAAI, Assistant Professor of Pediatrics, Medical Director Gores Family Allergy Center, Division of Clinical Immunology & Allergy
Children’s Hospital Los Angeles