Cellular Imaging Core

Services

The Imaging Scientist provides expert consultation on the design, execution and analysis of fixed and live cell imaging experiments. Please contact the Imaging Scientist directly to arrange access and training in the utilization of Core facilities.

Equipment and Software

The Cellular Imaging Core houses modern light microscopy and digital image processing equipment to support cell biology research at our facility as well as other institutions. Click here for details on our equipment and software.

  • Fee Structure
  • Published Data

Cellular Imaging Core Fee Structure

Principal Investigators based at The Saban Research Institute

  • Confocal Equipment (hourly) - $25 / hour (expert users)
  • Confocal Equipment (hourly) - $50 / hour (with assistance from Imaging Scientists)
  • Non-Confocal Equipment (monthly)
    • Unlimited access for all personnel - $100 / month
  • Non-Confocal Equipment (annually)
    • Unlimited access for all personnel - $800 / year

Access for Non-Hospital Researchers

Access to Cellular Imaging Core facilities for researchers at USC and other institutions can be arranged. Interested researchers should contact the Imaging Scientist to inquire about availability and rates.

Cellular Imaging Core Publications and Data 

3D Confocal

Vimentin-mediated signaling is required for IbeA+ E. coli K1 invasion of human brain microvascular endothelial cells.
2010. Chi F, Jong TD, Wang L, Ouyang Y, Wu C, Li W, Huang SH. Biochemical Journal 427(1):79-90. 

Calcium Imaging In Live Cells 

Escherichia coli K-1 Interaction with Human Brain Micro-vascular Endothelial Cells Triggers Phospholipase C-γ1 Activation Downstream of Phosphatidylinositol 3-Kinase
2003. Sukumaran SK, McNamara G, Prasadarao NV. Journal of Biological Chemistry 278(46):45753-45762. 

Confocal Image Quantitation

Hypothalamic neural projections are permanently disrupted in diet-induced obese rats.
2008. Bouret SG, Gorski JN, Patterson CM, Chen S, Levin BE, Simerly RB. Cell Metabolism 7(2):179-85.   

Fluorescence Image Quantitation

The Contribution of Bone Marrow–Derived Cells to the Tumor Vasculature in Neuroblastoma Is Matrix Metalloproteinase-9 Dependent
2005. Jodele S, Chantrain CF, Blavier L, Lutzko C, Crooks GM, Shimada H, Coussens LM, DeClerck YA. Cancer Research 65(8):3200-3208. 

Spectral Imaging

Hepatitis C Virus Causes Uncoupling of Mitotic Checkpoint and Chromosomal Polyploidy through the Rb Pathway
2009.  Machida K, Liu J-C, McNamara G, Levine A, Duan L, Lai MMC. Journal Of Virology 83(23):12590–12600.